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Literature summary for 1.5.1.20 extracted from
- Methionine biosynthesis (hog liver) (1971), Methods Enzymol., 17B, 371-378.
No PubMed abstract available
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 5,10-methylenetetrahydrofolate + FADH2 | Escherichia coli | - |
5-methyltetrahydrofolate + FAD | - |
? |  |
| 5,10-methylenetetrahydrofolate + FADH2 | Sus scrofa | first step of conversion of 5,10-methylenetetrahydrofolate to methionine | 5-methyltetrahydrofolate + FAD | - |
? | |
| 5,10-methylenetetrahydrofolate + FADH2 | Escherichia coli 113-3 | - |
5-methyltetrahydrofolate + FAD | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | - |
- |
- |
| Escherichia coli 113-3 | - |
- |
- |
| Sus scrofa | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Escherichia coli |
| 20fold purification | Sus scrofa |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Sus scrofa | - |
Storage Stability
| Storage Stability | Organism |
|---|---|
| -15°C, several months, stable | Sus scrofa |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 5,10-methylenetetrahydrofolate + FADH2 | - |
Escherichia coli | 5-methyltetrahydrofolate + FAD | - |
? | |
| 5,10-methylenetetrahydrofolate + FADH2 | first step of conversion of 5,10-methylenetetrahydrofolate to methionine | Sus scrofa | 5-methyltetrahydrofolate + FAD | - |
? | |
| 5,10-methylenetetrahydrofolate + FADH2 | - |
Escherichia coli 113-3 | 5-methyltetrahydrofolate + FAD | - |
? | |
| 5,10-methylenetetrahydrofolate + reduced acceptor | forward reaction: reduced acceptor is FADH2 | Escherichia coli | 5-methyltetrahydrofolate + oxidized acceptor | - |
r | |
| 5,10-methylenetetrahydrofolate + reduced acceptor | forward reaction: reduced acceptor is FADH2 | Sus scrofa | 5-methyltetrahydrofolate + oxidized acceptor | - |
r | |
| 5,10-methylenetetrahydrofolate + reduced acceptor | reverse reaction: menadione as electron acceptor | Escherichia coli | 5-methyltetrahydrofolate + oxidized acceptor | - |
r | |
| 5,10-methylenetetrahydrofolate + reduced acceptor | reverse reaction: menadione as electron acceptor | Sus scrofa | 5-methyltetrahydrofolate + oxidized acceptor | - |
r | |
| 5,10-methylenetetrahydrofolate + reduced acceptor | forward reaction: reduced acceptor is FADH2 | Escherichia coli 113-3 | 5-methyltetrahydrofolate + oxidized acceptor | - |
r | |
| 5,10-methylenetetrahydrofolate + reduced acceptor | reverse reaction: menadione as electron acceptor | Escherichia coli 113-3 | 5-methyltetrahydrofolate + oxidized acceptor | - |
r | |
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Release 2023.1 (January 2023)
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