Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Rattus norvegicus | 5829 | - |
cytosol | - |
Sus scrofa | 5829 | - |
soluble | - |
Rattus norvegicus | - |
- |
soluble | - |
Sus scrofa | - |
- |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
1-piperideine-2-carboxylate + NAD(P)H + H+ | Rattus norvegicus | - |
L-pipecolate + NAD(P)+ | - |
r | |
1-piperideine-2-carboxylate + NAD(P)H + H+ | Sus scrofa | - |
L-pipecolate + NAD(P)+ | - |
r | |
1-pyrroline-2-carboxylate + NAD(P)H + H+ | Rattus norvegicus | - |
L-proline + NAD(P)+ | - |
r | |
1-pyrroline-2-carboxylate + NAD(P)H + H+ | Sus scrofa | - |
L-proline + NAD(P)+ | - |
r |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Sus scrofa | - |
- |
- |
Purification (Comment) | Organism |
---|---|
native enzyme from kidney | Rattus norvegicus |
native enzyme partially from kidney | Sus scrofa |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | high enzyme activity | Rattus norvegicus | - |
brain cortex | - |
Rattus norvegicus | - |
cardiac muscle | - |
Rattus norvegicus | - |
kidney | - |
Rattus norvegicus | - |
kidney | high enzyme activity | Sus scrofa | - |
spleen | - |
Rattus norvegicus | - |
testis | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
1-piperideine-2-carboxylate + NAD(P)H + H+ | - |
Rattus norvegicus | L-pipecolate + NAD(P)+ | - |
r | |
1-piperideine-2-carboxylate + NAD(P)H + H+ | - |
Sus scrofa | L-pipecolate + NAD(P)+ | - |
r | |
1-pyrroline-2-carboxylate + NAD(P)H + H+ | - |
Rattus norvegicus | L-proline + NAD(P)+ | - |
r | |
1-pyrroline-2-carboxylate + NAD(P)H + H+ | - |
Sus scrofa | L-proline + NAD(P)+ | - |
r | |
additional information | the enzyme from kidney shows no activity with DELTA1-pyrroline-5-carboxylate and DELTA1-piperideine-6-carboxylate | Rattus norvegicus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ketimine reductase | - |
Rattus norvegicus |
ketimine reductase | - |
Sus scrofa |
P2C reductase | - |
Rattus norvegicus |
P2C reductase | - |
Sus scrofa |
P2C/Pyr2C reductase | - |
Rattus norvegicus |
P2C/Pyr2C reductase | - |
Sus scrofa |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
additional information | NADH and NADPH are equally effective as cofactor for the enzyme purified from rat kidney | Rattus norvegicus | |
additional information | the enzyme purified from porcine kidney shows equal activity with NADPH and NADH | Sus scrofa | |
NADH | - |
Rattus norvegicus | |
NADH | - |
Sus scrofa | |
NADPH | - |
Rattus norvegicus | |
NADPH | - |
Sus scrofa |