Literature summary for 1.4.9.1 extracted from

Sun, D.; Chen, Z.W.; Mathews, F.S.; Davidson, V.L.
Mutation of alphaPhe55 of methylamine dehydrogenase alters the reorganization energy and electronic coupling for its electron transfer reaction with amicyanin (2002), Biochemistry, 41, 13926-13933.

Crystallization (Commentary)

Crystallization (Comment)	Organism
sitting drop method, crystal structure of alphaF55A in complex with its electron acceptors, amicyanin and cytochrome c-551i. Little difference in the overal structure is seen, relative to the native complex. There are significant changes in the solvent content of the active site and substrate channel. Crystal structure of alphaF55A with phenylhydrazine covalently bound to tryptophan tryptophylquinone in the active site	Paracoccus denitrificans

Crystallization (Comment)

Organism

sitting drop method, crystal structure of alphaF55A in complex with its electron acceptors, amicyanin and cytochrome c-551i. Little difference in the overal structure is seen, relative to the native complex. There are significant changes in the solvent content of the active site and substrate channel. Crystal structure of alphaF55A with phenylhydrazine covalently bound to tryptophan tryptophylquinone in the active site

Paracoccus denitrificans

Protein Variants

Protein Variants	Comment	Organism
alphaF55A	mutation increases the rate of the electron transfer reaction from the fully reduced tryptophan tryptophylquinone tryptophan tryptophylquinone methylamine dehydrogenase to amicyanin. Little difference in the overal structure of alphaF55A in complex with its electron acceptors, amicyanin and cytochrome c-551i, relative to the native complex. There are significant changes in the solvent content of the active site and substrate channel	Paracoccus denitrificans

Organism

Organism	UniProt	Comment	Textmining
Paracoccus denitrificans	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
methylamine + acceptor + H2O	acceptor: amicyanin	Paracoccus denitrificans	formaldehyde + NH3 + reduced acceptor	-	?

Synonyms

Synonyms	Comment	Organism
MADH	-	Paracoccus denitrificans

Cofactor

Cofactor	Comment	Organism	Structure
tryptophan tryptophylquinone	-	Paracoccus denitrificans