Activating Compound | Comment | Organism | Structure |
---|---|---|---|
3-Hydroxyanthranilate | 145% increase in pyridoxine 5-phosphate oxidase activity, 28% increase in pyridoxamine 5-phosphate oxidase activity | Rattus norvegicus | |
3-hydroxykynurenine | 125% increase in pyridoxine 5-phosphate oxidase activity, 20% increase in pyridoxamine 5-phosphate oxidase activity | Rattus norvegicus | |
5-hydroxyindolacetate | 125% increase in pyridoxine 5-phosphate oxidase activity, 9% increase in pyridoxamine 5-phosphate oxidase activity | Rattus norvegicus | |
5-hydroxytryptamine | 20% increase in pyridoxamine 5-phosphate oxidase activity | Rattus norvegicus | |
tryptamine | 27% increase in pyridoxamine 5-phosphate oxidase activity | Rattus norvegicus | |
xanthurenate | 21% increase in pyridoxine 5-phosphate oxidase activity | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | no inhibition by tryptophan metabolites | Rattus norvegicus | |
pyridoxamine 5'-phosphate | substrate inhibition above 0.0006 mM | Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00092 | - |
pyridoxine 5'-phosphate | - |
Rattus norvegicus | |
0.01 | - |
pyridoxamine 5'-phosphate | - |
Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Rattus norvegicus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.138 | - |
- |
Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
pyridoxamine 5'-phosphate + H2O + O2 | - |
Rattus norvegicus | pyridoxal 5'-phosphate + NH3 + H2O2 | - |
? | |
pyridoxine 5'-phosphate + FMN | - |
Rattus norvegicus | pyridoxal 5'-phosphate + FMNH2 | - |
? |