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Literature summary for 1.4.3.4 extracted from

  • Yagodina, O.
    Enzymological characteristic of monoamine oxidase from the visual ganglia of the Pacific squid Todarodes pacificus (2009), Dokl. Biochem. Biophys., 428, 284-287.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
chlorgilin
-
Todarodes pacificus
Deprenyl
-
Todarodes pacificus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.12
-
serotonin pH not specified in the publication, temperature not specified in the publication Todarodes pacificus
4.53
-
tryptamine pH not specified in the publication, temperature not specified in the publication Todarodes pacificus
5.61
-
histamine pH not specified in the publication, temperature not specified in the publication Todarodes pacificus
6.14
-
tyramine pH not specified in the publication, temperature not specified in the publication Todarodes pacificus
6.34
-
Phenylethylamine pH not specified in the publication, temperature not specified in the publication Todarodes pacificus
6.81
-
benzylamine pH not specified in the publication, temperature not specified in the publication Todarodes pacificus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2-phenylethylamine + H2O + O2 Todarodes pacificus
-
2-phenylethanal + NH3 + H2O2
-
?
benzylamine + H2O + O2 Todarodes pacificus
-
benzylaldehyde + NH3 + H2O2
-
?
histamine + H2O + O2 Todarodes pacificus
-
?
-
?
serotonin + H2O + O2 Todarodes pacificus
-
(5-hydroxy-1H-indol-3-yl)acetaldehyde + NH3 + H2O2
-
?
tryptamine + H2O + O2 Todarodes pacificus
-
(1H-indol-3-yl)acetaldehyde + NH3 + H2O2
-
?
tyramine + H2O + O2 Todarodes pacificus
-
?
-
?

Organism

Organism UniProt Comment Textmining
Todarodes pacificus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-phenylethylamine + H2O + O2
-
Todarodes pacificus 2-phenylethanal + NH3 + H2O2
-
?
benzylamine + H2O + O2
-
Todarodes pacificus benzylaldehyde + NH3 + H2O2
-
?
histamine + H2O + O2
-
Todarodes pacificus ?
-
?
serotonin + H2O + O2
-
Todarodes pacificus (5-hydroxy-1H-indol-3-yl)acetaldehyde + NH3 + H2O2
-
?
tryptamine + H2O + O2
-
Todarodes pacificus (1H-indol-3-yl)acetaldehyde + NH3 + H2O2
-
?
tyramine + H2O + O2
-
Todarodes pacificus ?
-
?

Synonyms

Synonyms Comment Organism
MAO
-
Todarodes pacificus
monoamine:O2 oxidoreductase, deaminating
-
Todarodes pacificus

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
additional information
-
additional information inhibition kinetics and specificity, overview Todarodes pacificus

General Information

General Information Comment Organism
physiological function MAO maintains physiological level of mediators in the presynaptic nerve terminal. The biological role of MAO is associated with the regulation of the level of mediators in nerve structures and, therefore, with different functions of the nervous system Todarodes pacificus