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Literature summary for 1.4.3.4 extracted from

  • Saba, W.; Valette, H.; Peyronneau, M.A.; Bramoulle, Y.; Coulon, C.; Curet, O.; George, P.; Dolle, F.; Bottlaender, M.
    [(11)C]SL25.1188, a new reversible radioligand to study the monoamine oxidase type B with PET: preclinical characterisation in nonhuman primate (2009), Synapse, 64, 61-69.
    View publication on PubMed
Search for more literature for 1.4.3.4

Inhibitors

Inhibitors Comment Organism Structure
(S)-5-methoxymethyl-3-[6-(4,4,4-trifluorobutoxy)-benzo[d]isoxazol-3-yl]-oxazolidin-2-one SL25.1188, inhibits MAO-B in the brain with 50% unspecific binding, overview Papio sp.
Clorgyline selective inhibition of MAO-A Papio sp.
Deprenyl selective inhibition of MAO-B Papio sp.
lazabemide selective inhibition of MAO-B Papio sp.

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrial outer membrane
-
 Papio sp. 5741
-

Organism

Organism UniProt Comment Textmining
Papio sp.
-
 baboon
-

Source Tissue

Source Tissue Comment Organism Textmining
brain in the brain MAO-B predominates and is associated with both glia and neurons, distribution in putamen, caudate nucleus, thalamus, hippocampus, cerebellum, temporal cortex, occipital cortex, parietal cortex, frontal cortex, white matter, and pons Papio sp.
-
liver
-
 Papio sp.
-

Synonyms

Synonyms Comment Organism
MAO-A
-
 Papio sp.
MAO-B
-
 Papio sp.

Cofactor

Cofactor Comment Organism Structure
flavin
-
 Papio sp.