Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.4.3.4 extracted from

  • Buckholtz, J.W.; Meyer-Lindenberg, A.
    MAOA and the neurogenetic architecture of human aggression (2008), Trends Neurosci., 31, 120-129.
    View publication on PubMed

Application

Application Comment Organism
medicine MAOA-L (the low-expressing allele of the MAOA u-variable-number tandem repeat), by causing an ontogenic excess of 5-hydroxytryptamine, labilizes critical neural circuitry for social evaluation and emotion regulation, thereby amplifying the effects of adverse early-life experience and creating deleterious sociocognitive biases Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens P21397
-
-

Synonyms

Synonyms Comment Organism
MAOA
-
Homo sapiens