Literature summary for 1.4.3.4 extracted from

Prevot, D.; Soltesz, Z.; Abello, V.; Wanecq, E.; Valet, P.; Unzeta, M.; Carpene, C.
Prolonged treatment with aminoguanidine strongly inhibits adipocyte semicarbazide-sensitive amine oxidase and slightly reduces fat deposition in obese Zucker rats (2007), Pharmacol. Res., 56, 70-79.

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Application

Application	Comment	Organism
medicine	aminoguanidine may be useful for treating obesity via its SSAO blocking properties	Rattus norvegicus

Inhibitors

Inhibitors	Comment	Organism	Structure
aminoguanidine	complete impairment of SSAO activity produced by aminoguanidine-treatment in obese rats is likely responsible for a weak limitation of fat deposition. Aminoguanidine may be useful for treating obesity via its SSAO blocking properties	Rattus norvegicus

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
adipocyte	-	Rattus norvegicus	-

Synonyms

Synonyms	Comment	Organism
semicarbazide-sensitive amine oxidase	-	Rattus norvegicus

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Release 2023.1 (January 2023)