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Literature summary for 1.4.3.4 extracted from

  • Wu, Y.H.; Fischer, D.F.; Swaab, D.F.
    A promoter polymorphism in the monoamine oxidase A gene is associated with the pineal MAOA activity in Alzheimers disease patients (2007), Brain Res., 1167, 13-19.
    View publication on PubMed
Search for more literature for 1.4.3.4

Organism

Organism UniProt Comment Textmining
Homo sapiens P21397
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Source Tissue

Source Tissue Comment Organism Textmining
brain MAOA activity and gene expression is upregulated in different brain areas of Alzheimer's disease patients, including the pineal gland. Alzheimer's disease patients carrying long MAOA-VNTR genotype (consisting of 3.5- or 4-repeat alleles) show higher MAOA gene expression and activity than the short-genotyped Alzheimer's disease patients (i.e., 3-repeat allele). MAOA-VNTR affects the activity and gene expression of MAOA in the brain of Alzheimer's disease patients, and is involved in the changes of monoamine metabolism Homo sapiens
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pineal gland MAOA activity and gene expression is upregulated in different brain areas of Alzheimer's disease patients, including the pineal gland. Increased pineal MAOA activity might contribute to the reduced pineal melatonin production in Alzheimer's disease. Alzheimer's disease patients carrying long MAOA-VNTR genotype (consisting of 3.5- or 4-repeat alleles) show higher MAOA gene expression and activity than the short-genotyped Alzheimer's disease patients (i.e., 3-repeat allele). MAOA-VNTR affects the activity and gene expression of MAOA in the brain of Alzheimer's disease patients, and is involved in the changes of monoamine metabolism Homo sapiens
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Synonyms

Synonyms Comment Organism
MAOA
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 Homo sapiens
monoamine oxidase A
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 Homo sapiens