Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.4.3.4 extracted from

  • Herraiz, T.; Chaparro, C.
    Human monoamine oxidase enzyme inhibition by coffee and beta-carbolines norharman and harman isolated from coffee (2006), Life Sci., 78, 795-802.
    View publication on PubMed

Application

Application Comment Organism
medicine the enzyme is a target for antidepressant and neuroprotective drugs Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
harman inhibition of MAO A Homo sapiens
additional information coffee contains compounds acting as reversible and competitive inhibitors for MAO A; coffee contains compounds acting as reversible and competitive inhibitors for MAO B Homo sapiens
norharman inhibition of MAO A; inhibition of MAO B Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens the enzyme is involved in brain and peripheral oxidative catabolism of neurotransmitters and xenobiotic amines ?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens P21397
-
-
Homo sapiens P27338
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the enzyme is involved in brain and peripheral oxidative catabolism of neurotransmitters and xenobiotic amines Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
MAO A
-
Homo sapiens
MAO B
-
Homo sapiens