Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | both the MAO-A and MAO-B isoforms, deposited in the Protein Data bank as the 2BXR and 1GOS models, respectively, are considered in a computational sttudy performed with docking techniques to explain the selective inhibitory activity towards the MAO-A and MAO-B enzymes; both the MAO-A and MAO-B isoforms, deposited in the Protein Data bank as the 2BXR and 1GOS models, respectively, are considered in a computational sttudy performed with docking techniques to explain the selective inhibitory activity towards the MAO-A and MAO-B enzymes | Homo sapiens | |
N,N'-(1R,2S)-cyclohexane-1,2-diylbis(2-oxo-2H-chromene-3-carboxamide) | - |
Bos taurus | |
N,N'-1,2-phenylenebis(2-oxo-2H-chromene-3-carboxamide) | - |
Bos taurus | |
N,N'-1,4-phenylenebis(2-oxo-2H-chromene-3-carboxamide) | - |
Bos taurus | |
N,N'-butane-1,4-diylbis(2-oxo-2H-chromene-3-carboxamide) | potent inhibitor of MAO-A with high selectivity towards MAO-B; potent inhibitor of MAO-A with high selectivity towards MAO-B | Bos taurus | |
N,N'-butane-1,4-diylbis(7-methoxy-2-oxo-2H-chromene-3-carboxamide) | - |
Bos taurus | |
N,N'-ethane-1,2-diylbis(2-oxo-2H-chromene-3-carboxamide) | - |
Bos taurus | |
N,N'-hexane-1,6-diylbis(2-oxo-2H-chromene-3-carboxamide) | potent inhibitor of MAO-A with high selectivity towards MAO-B; potent inhibitor of MAO-A with high selectivity towards MAO-B | Bos taurus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Bos taurus | 5739 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | P21398 | - |
- |
Bos taurus | P56560 | - |
- |
Homo sapiens | P21397 | - |
- |
Homo sapiens | P27338 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Bos taurus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
kynuramine + H2O + O2 | - |
Bos taurus | 3-(2-aminophenyl)-3-oxopropanal + NH3 + H2O2 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
MAO A | - |
Homo sapiens |
MAO A | - |
Bos taurus |
MAO B | - |
Homo sapiens |
MAO B | - |
Bos taurus |