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Literature summary for 1.4.3.4 extracted from

  • Ucar, G.
    Substrate specificities of monoamine oxidase isoforms (2002), FABAD J. Pharm. Sci., 27, 149-156.
No PubMed abstract available
Search for more literature for 1.4.3.4

Inhibitors

Inhibitors Comment Organism Structure
Clorgyline
-
 Rattus norvegicus
Pargyline
-
 Homo sapiens
Pargyline
-
 Rattus norvegicus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.02
-
 tyramine 37°C Rattus norvegicus
0.06
-
 tyramine 37°C Rattus norvegicus
0.19
-
 benzylamine
-
 Homo sapiens
0.44
-
 serotonin
-
 Rattus norvegicus
0.58
-
 benzylamine 37°C Rattus norvegicus
1.42
-
 benzylamine 37°C Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
 Rattus norvegicus 5739
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
blood platelet
-
 Homo sapiens
-
liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
benzylamine + H2O + O2
-
 Homo sapiens benzaldehyde + NH3 + H2O2
-
 ?
benzylamine + H2O + O2
-
 Rattus norvegicus benzaldehyde + NH3 + H2O2
-
 ?
additional information no significant activity with serotonin Rattus norvegicus ?
-
 ?
serotonin + H2O + O2
-
 Rattus norvegicus (5-hydroxy-1H-indol-3-yl)acetaldehyde + NH3 + H2O2
-
 ?
tyramine + H2O + O2
-
 Rattus norvegicus (4-hydroxyphenyl)acetaldehyde + NH3 + H2O2
-
 ?

Synonyms

Synonyms Comment Organism
MAO-A
-
 Rattus norvegicus
MAO-B
-
 Homo sapiens
MAO-B
-
 Rattus norvegicus