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Literature summary for 1.4.3.4 extracted from
- Monoamine oxidase from beef liver mitochondria: simplified isolation procedure, properties, and determination of its cysteinyl flavin content (1979), Arch. Biochem. Biophys., 192, 128-137.
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| mitochondrion | - |
Bos taurus | 5739 | - |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 62000 | - |
2 * 62000, SDS-PAGE in presence of mercaptoethanol | Bos taurus |
| 146000 | - |
calculation on basis of flavin content | Bos taurus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bos taurus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Bos taurus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Bos taurus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
- |
Bos taurus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 2-phenylethylamine + H2O + O2 | MAO-B selective substrate | Bos taurus | 2-phenylethanal + NH3 + H2O2 | - |
? |  |
| benzylamine + H2O + O2 | MAO-B selective substrate | Bos taurus | benzaldehyde + NH3 + H2O2 | - |
? | |
| dopamine + H2O + O2 | nonselective substrate | Bos taurus | (3,4-dihydroxyphenyl)acetaldehyde + NH3 + H2O2 | - |
? | |
| RCH2NH2 + H2O + O2 | 5-hydroxytryptamine, MAO-A selective substrate | Bos taurus | RCHO + NH3 + H2O2 | - |
? | |
| tryptamine + H2O + O2 | - |
Bos taurus | 1H-indol-3-yl-acetaldehyde + NH3 + H2O2 | - |
? | |
| tyramine + H2O + O2 | nonselective substrate | Bos taurus | (4-hydroxyphenyl)acetaldehyde + NH3 + H2O2 | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| dimer | 2 * 62000, SDS-PAGE in presence of mercaptoethanol | Bos taurus |
Turnover Number [1/s]
| Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 7 | 7.83 | benzylamine | - |
Bos taurus | |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| flavin | contains 2 subunits: only one of which possesses covalently linked flavin | Bos taurus | |
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Release 2023.1 (January 2023)
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