BRENDA - Enzyme Database
show all sequences of 1.4.3.21

Characterization of two amine oxidases from Aspergillus carbonarius AIU 205

Sugawara, A.; Matsui, D.; Yamada, M.; Asano, Y.; Isobe, K.; J. Biosci. Bioeng. 119, 629-635 (2015) View publication on PubMed

Data extracted from this reference:

Inhibitors
Inhibitors
Commentary
Organism
Structure
8-hydroxyquinoline
strong inhibition at 1 mM
Aspergillus carbonarius
CuCl2
strong inhibition at 1 mM
Aspergillus carbonarius
hydrazine
complete inhibition at 1 mM
Aspergillus carbonarius
hydroxylamine
complete inhibition at 1 mM
Aspergillus carbonarius
Iproniazid
nearly complete inhibition at 1 mM
Aspergillus carbonarius
isoniazid
nearly complete inhibition at 1 mM
Aspergillus carbonarius
additional information
not inhibited by MgCl2, MnCl2, CoCl2, ZnCl2, FeCl3, sodium azide, N-ethylmaleimide, and iodoacetate
Aspergillus carbonarius
phenylhydrazine
complete inhibition at 1 mM
Aspergillus carbonarius
Semicarbazide
nearly complete inhibition at 1 mM
Aspergillus carbonarius
Molecular Weight [Da]
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
69100
-
enzyme III, gel filtration
Aspergillus carbonarius
130000
-
enzyme II, gel filtration
Aspergillus carbonarius
Organism
Organism
UniProt
Commentary
Textmining
Aspergillus carbonarius
-
-
-
Aspergillus carbonarius AIU 205
-
-
-
Purification (Commentary)
Purification (Commentary)
Organism
DEAE-Toyopearl column chromatography, and phenyl-Toyopearl column chromatography
Aspergillus carbonarius
Source Tissue
Source Tissue
Commentary
Organism
Textmining
mycelium
-
Aspergillus carbonarius
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
Substrate Product ID
1,4-diaminobutane + H2O + O2
enzyme II shows 23% activity and enzyme III 12% activity compared to 4-aminobutanamide
742933
Aspergillus carbonarius
?
-
-
-
?
1,5-diaminopentane + H2O + O2
enzyme II shows 5% activity and enzyme III 31% activity compared to 4-aminobutanamide
742933
Aspergillus carbonarius
?
-
-
-
?
2-phenylethylamine + H2O + O2
enzyme II shows 134% activity and enzyme III 591% activity compared to 4-aminobutanamide
742933
Aspergillus carbonarius
phenylacetaldehyde + NH3 + H2O2
-
-
-
?
3-aminopentanamide + H2O + O2
enzyme II shows 214% activity and enzyme III 11% activity compared to 4-aminobutanamide
742933
Aspergillus carbonarius
3-oxopentanamide + NH3 + H2O2
-
-
-
?
4-amino-1-butanol + H2O + O2
enzyme II shows 525% activity and enzyme III 267% activity compared to 4-aminobutanamide
742933
Aspergillus carbonarius
4-hydroxybutanal + NH3 + H2O2
-
-
-
?
4-aminobutanamide + H2O + O2
100% activity
742933
Aspergillus carbonarius
4-oxobutanamide + NH3 + H2O2
-
-
-
?
4-aminobutyric acid + H2O + O2
enzyme II shows no activity and enzyme III 10% activity compared to 4-aminobutanamide
742933
Aspergillus carbonarius
4-oxobutanoate + NH3 + H2O2
-
-
-
?
4-phenylbutylamine + H2O + O2
enzyme II shows 122% activity and enzyme III 493% activity compared to 4-aminobutanamide
742933
Aspergillus carbonarius
4-phenylbutanal + NH3 + H2O2
-
-
-
?
4-phenylbutylamine + H2O + O2
enzyme II shows 122% activity and enzyme III 493% activity compared to 4-aminobutanamide
742933
Aspergillus carbonarius AIU 205
4-phenylbutanal + NH3 + H2O2
-
-
-
?
5-amino-1-pentanol + H2O + O2
enzyme II shows 86% activity and enzyme III 388% activity compared to 4-aminobutanamide
742933
Aspergillus carbonarius
5-hydroxypentanal + NH3 + H2O2
-
-
-
?
5-aminopentanoic acid + H2O + O2
enzyme II shows 3% activity and enzyme III 7% activity compared to 4-aminobutanamide
742933
Aspergillus carbonarius
5-oxopentanoate + NH3 + H2O2
-
-
-
?
5-hydroxytryptamine + H2O + O2
enzyme II shows no activity and enzyme III 6% activity compared to 4-aminobutanamide
742933
Aspergillus carbonarius
?
-
-
-
?
5-hydroxytryptamine + H2O + O2
enzyme II shows no activity and enzyme III 6% activity compared to 4-aminobutanamide
742933
Aspergillus carbonarius AIU 205
?
-
-
-
?
benzylamine + H2O + O2
enzyme II shows 4% activity and enzyme III 157% activity compared to 4-aminobutanamide
742933
Aspergillus carbonarius
benzaldehyde + NH3 + H2O2
-
-
-
?
benzylamine + H2O + O2
enzyme II shows 4% activity and enzyme III 157% activity compared to 4-aminobutanamide
742933
Aspergillus carbonarius AIU 205
benzaldehyde + NH3 + H2O2
-
-
-
?
ethylamine + H2O + O2
enzyme II shows 1124% activity and enzyme III 119% activity compared to 4-aminobutanamide
742933
Aspergillus carbonarius
acetaldehyde + NH3 + H2O2
-
-
-
?
histamine + H2O + O2
enzyme II shows 6% activity and enzyme III 322% activity compared to 4-aminobutanamide
742933
Aspergillus carbonarius
1H-imidazol-4-ylacetaldehyde + NH3 + H2O2
-
-
-
?
histamine + H2O + O2
enzyme II shows 6% activity and enzyme III 322% activity compared to 4-aminobutanamide
742933
Aspergillus carbonarius AIU 205
1H-imidazol-4-ylacetaldehyde + NH3 + H2O2
-
-
-
?
additional information
no activity with dopamine, 2-aminoacetic acid, 3-aminopropanoic aid, L-Arg, L-Orn, L-Lys, L-Phe, and D-Lys
742933
Aspergillus carbonarius
?
-
-
-
?
additional information
no activity with dopamine, 2-aminoacetic acid, 3-aminopropanoic aid, L-Arg, L-Orn, L-Lys, L-Phe, and D-Lys
742933
Aspergillus carbonarius AIU 205
?
-
-
-
?
n-butylamine + H2O + O2
enzyme II shows 368% activity and enzyme III 454% activity compared to 4-aminobutanamide
742933
Aspergillus carbonarius
butanal + NH3 + H2O2
-
-
-
?
n-hexylamine + H2O + O2
enzyme II shows 244% activity and enzyme III 589% activity compared to 4-aminobutanamide
742933
Aspergillus carbonarius
hexanal + NH3 + H2O2
-
-
-
?
n-pentylamine + H2O + O2
enzyme II shows 314% activity and enzyme III 596% activity compared to 4-aminobutanamide
742933
Aspergillus carbonarius
pentanal + NH3 + H2O2
-
-
-
?
n-propylamine + H2O + O2
enzyme II shows 515% activity and enzyme III 201% activity compared to 4-aminobutanamide
742933
Aspergillus carbonarius
propanal + NH3 + H2O2
-
-
-
?
Nalpha-benzyloxycarbony-L-lysine + H2O + O2
enzyme II shows 3% activity and enzyme III 12% activity compared to 4-aminobutanamide
742933
Aspergillus carbonarius
?
-
-
-
?
Nalpha-Z-D-lysine + H2O + O2
enzyme II shows no activity and enzyme III 10% activity compared to 4-aminobutanamide
742933
Aspergillus carbonarius
?
-
-
-
?
tryptamine + H2O + O2
enzyme II shows 4% activity and enzyme III 175% activity compared to 4-aminobutanamide
742933
Aspergillus carbonarius
(1H-indol-3-yl)acetaldehyde + NH3 + H2O2
-
-
-
?
Subunits
Subunits
Commentary
Organism
homodimer
2 * 67100, native enzyme II, SDS-PAGE
Aspergillus carbonarius
monomer
1 * 65000, native enzyme III, SDS-PAGE
Aspergillus carbonarius
Synonyms
Synonyms
Commentary
Organism
copper-containing amine oxidase
-
Aspergillus carbonarius
Temperature Optimum [°C]
Temperature Optimum [°C]
Temperature Optimum Maximum [°C]
Commentary
Organism
40
-
enzyme III, isoelectric focusing
Aspergillus carbonarius
45
-
enzyme II, isoelectric focusing
Aspergillus carbonarius
Temperature Stability [°C]
Temperature Stability Minimum [°C]
Temperature Stability Maximum [°C]
Commentary
Organism
20
50
when enzymes II and III are incubated at pH 7.0 for 30 min at 20-60°C without a substrate, more than 85% of the original activity remains below 40°C in both enzymes. At 50°C, enzyme II remains 60% of enzyme activity, while enzyme III loses 90% of its original activity
Aspergillus carbonarius
pH Optimum
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
7.5
-
enzyme III
Aspergillus carbonarius
8.5
-
enzyme II
Aspergillus carbonarius
pH Stability
pH Stability
pH Stability Maximum
Commentary
Organism
5
8.5
when enzymes II and III are incubated at 40°C for 30 min in a pH range from 5.0 to 8.5 without a substrate, enzymes II and III remain at more than 80% of their original activity levels between pH 7.0 and 8.5 as well as between pH 6.5 and 8.5
Aspergillus carbonarius
pI Value
Organism
Commentary
pI Value Maximum
pI Value
Aspergillus carbonarius
enzyme III, isoelectric focusing
-
5
Aspergillus carbonarius
enzyme II, isoelectric focusing
-
5.3
Inhibitors (protein specific)
Inhibitors
Commentary
Organism
Structure
8-hydroxyquinoline
strong inhibition at 1 mM
Aspergillus carbonarius
CuCl2
strong inhibition at 1 mM
Aspergillus carbonarius
hydrazine
complete inhibition at 1 mM
Aspergillus carbonarius
hydroxylamine
complete inhibition at 1 mM
Aspergillus carbonarius
Iproniazid
nearly complete inhibition at 1 mM
Aspergillus carbonarius
isoniazid
nearly complete inhibition at 1 mM
Aspergillus carbonarius
additional information
not inhibited by MgCl2, MnCl2, CoCl2, ZnCl2, FeCl3, sodium azide, N-ethylmaleimide, and iodoacetate
Aspergillus carbonarius
phenylhydrazine
complete inhibition at 1 mM
Aspergillus carbonarius
Semicarbazide
nearly complete inhibition at 1 mM
Aspergillus carbonarius
Molecular Weight [Da] (protein specific)
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
69100
-
enzyme III, gel filtration
Aspergillus carbonarius
130000
-
enzyme II, gel filtration
Aspergillus carbonarius
Purification (Commentary) (protein specific)
Commentary
Organism
DEAE-Toyopearl column chromatography, and phenyl-Toyopearl column chromatography
Aspergillus carbonarius
Source Tissue (protein specific)
Source Tissue
Commentary
Organism
Textmining
mycelium
-
Aspergillus carbonarius
-
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
ID
1,4-diaminobutane + H2O + O2
enzyme II shows 23% activity and enzyme III 12% activity compared to 4-aminobutanamide
742933
Aspergillus carbonarius
?
-
-
-
?
1,5-diaminopentane + H2O + O2
enzyme II shows 5% activity and enzyme III 31% activity compared to 4-aminobutanamide
742933
Aspergillus carbonarius
?
-
-
-
?
2-phenylethylamine + H2O + O2
enzyme II shows 134% activity and enzyme III 591% activity compared to 4-aminobutanamide
742933
Aspergillus carbonarius
phenylacetaldehyde + NH3 + H2O2
-
-
-
?
3-aminopentanamide + H2O + O2
enzyme II shows 214% activity and enzyme III 11% activity compared to 4-aminobutanamide
742933
Aspergillus carbonarius
3-oxopentanamide + NH3 + H2O2
-
-
-
?
4-amino-1-butanol + H2O + O2
enzyme II shows 525% activity and enzyme III 267% activity compared to 4-aminobutanamide
742933
Aspergillus carbonarius
4-hydroxybutanal + NH3 + H2O2
-
-
-
?
4-aminobutanamide + H2O + O2
100% activity
742933
Aspergillus carbonarius
4-oxobutanamide + NH3 + H2O2
-
-
-
?
4-aminobutyric acid + H2O + O2
enzyme II shows no activity and enzyme III 10% activity compared to 4-aminobutanamide
742933
Aspergillus carbonarius
4-oxobutanoate + NH3 + H2O2
-
-
-
?
4-phenylbutylamine + H2O + O2
enzyme II shows 122% activity and enzyme III 493% activity compared to 4-aminobutanamide
742933
Aspergillus carbonarius
4-phenylbutanal + NH3 + H2O2
-
-
-
?
4-phenylbutylamine + H2O + O2
enzyme II shows 122% activity and enzyme III 493% activity compared to 4-aminobutanamide
742933
Aspergillus carbonarius AIU 205
4-phenylbutanal + NH3 + H2O2
-
-
-
?
5-amino-1-pentanol + H2O + O2
enzyme II shows 86% activity and enzyme III 388% activity compared to 4-aminobutanamide
742933
Aspergillus carbonarius
5-hydroxypentanal + NH3 + H2O2
-
-
-
?
5-aminopentanoic acid + H2O + O2
enzyme II shows 3% activity and enzyme III 7% activity compared to 4-aminobutanamide
742933
Aspergillus carbonarius
5-oxopentanoate + NH3 + H2O2
-
-
-
?
5-hydroxytryptamine + H2O + O2
enzyme II shows no activity and enzyme III 6% activity compared to 4-aminobutanamide
742933
Aspergillus carbonarius
?
-
-
-
?
5-hydroxytryptamine + H2O + O2
enzyme II shows no activity and enzyme III 6% activity compared to 4-aminobutanamide
742933
Aspergillus carbonarius AIU 205
?
-
-
-
?
benzylamine + H2O + O2
enzyme II shows 4% activity and enzyme III 157% activity compared to 4-aminobutanamide
742933
Aspergillus carbonarius
benzaldehyde + NH3 + H2O2
-
-
-
?
benzylamine + H2O + O2
enzyme II shows 4% activity and enzyme III 157% activity compared to 4-aminobutanamide
742933
Aspergillus carbonarius AIU 205
benzaldehyde + NH3 + H2O2
-
-
-
?
ethylamine + H2O + O2
enzyme II shows 1124% activity and enzyme III 119% activity compared to 4-aminobutanamide
742933
Aspergillus carbonarius
acetaldehyde + NH3 + H2O2
-
-
-
?
histamine + H2O + O2
enzyme II shows 6% activity and enzyme III 322% activity compared to 4-aminobutanamide
742933
Aspergillus carbonarius
1H-imidazol-4-ylacetaldehyde + NH3 + H2O2
-
-
-
?
histamine + H2O + O2
enzyme II shows 6% activity and enzyme III 322% activity compared to 4-aminobutanamide
742933
Aspergillus carbonarius AIU 205
1H-imidazol-4-ylacetaldehyde + NH3 + H2O2
-
-
-
?
additional information
no activity with dopamine, 2-aminoacetic acid, 3-aminopropanoic aid, L-Arg, L-Orn, L-Lys, L-Phe, and D-Lys
742933
Aspergillus carbonarius
?
-
-
-
?
additional information
no activity with dopamine, 2-aminoacetic acid, 3-aminopropanoic aid, L-Arg, L-Orn, L-Lys, L-Phe, and D-Lys
742933
Aspergillus carbonarius AIU 205
?
-
-
-
?
n-butylamine + H2O + O2
enzyme II shows 368% activity and enzyme III 454% activity compared to 4-aminobutanamide
742933
Aspergillus carbonarius
butanal + NH3 + H2O2
-
-
-
?
n-hexylamine + H2O + O2
enzyme II shows 244% activity and enzyme III 589% activity compared to 4-aminobutanamide
742933
Aspergillus carbonarius
hexanal + NH3 + H2O2
-
-
-
?
n-pentylamine + H2O + O2
enzyme II shows 314% activity and enzyme III 596% activity compared to 4-aminobutanamide
742933
Aspergillus carbonarius
pentanal + NH3 + H2O2
-
-
-
?
n-propylamine + H2O + O2
enzyme II shows 515% activity and enzyme III 201% activity compared to 4-aminobutanamide
742933
Aspergillus carbonarius
propanal + NH3 + H2O2
-
-
-
?
Nalpha-benzyloxycarbony-L-lysine + H2O + O2
enzyme II shows 3% activity and enzyme III 12% activity compared to 4-aminobutanamide
742933
Aspergillus carbonarius
?
-
-
-
?
Nalpha-Z-D-lysine + H2O + O2
enzyme II shows no activity and enzyme III 10% activity compared to 4-aminobutanamide
742933
Aspergillus carbonarius
?
-
-
-
?
tryptamine + H2O + O2
enzyme II shows 4% activity and enzyme III 175% activity compared to 4-aminobutanamide
742933
Aspergillus carbonarius
(1H-indol-3-yl)acetaldehyde + NH3 + H2O2
-
-
-
?
Subunits (protein specific)
Subunits
Commentary
Organism
homodimer
2 * 67100, native enzyme II, SDS-PAGE
Aspergillus carbonarius
monomer
1 * 65000, native enzyme III, SDS-PAGE
Aspergillus carbonarius
Temperature Optimum [°C] (protein specific)
Temperature Optimum [°C]
Temperature Optimum Maximum [°C]
Commentary
Organism
40
-
enzyme III, isoelectric focusing
Aspergillus carbonarius
45
-
enzyme II, isoelectric focusing
Aspergillus carbonarius
Temperature Stability [°C] (protein specific)
Temperature Stability Minimum [°C]
Temperature Stability Maximum [°C]
Commentary
Organism
20
50
when enzymes II and III are incubated at pH 7.0 for 30 min at 20-60°C without a substrate, more than 85% of the original activity remains below 40°C in both enzymes. At 50°C, enzyme II remains 60% of enzyme activity, while enzyme III loses 90% of its original activity
Aspergillus carbonarius
pH Optimum (protein specific)
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
7.5
-
enzyme III
Aspergillus carbonarius
8.5
-
enzyme II
Aspergillus carbonarius
pH Stability (protein specific)
pH Stability
pH Stability Maximum
Commentary
Organism
5
8.5
when enzymes II and III are incubated at 40°C for 30 min in a pH range from 5.0 to 8.5 without a substrate, enzymes II and III remain at more than 80% of their original activity levels between pH 7.0 and 8.5 as well as between pH 6.5 and 8.5
Aspergillus carbonarius
pI Value (protein specific)
Organism
Commentary
pI Value Maximum
pI Value
Aspergillus carbonarius
enzyme III, isoelectric focusing
-
5
Aspergillus carbonarius
enzyme II, isoelectric focusing
-
5.3
Other publictions for EC 1.4.3.21
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Synonyms
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
743003
Gross
Copper amine oxidase 8 regula ...
Arabidopsis thaliana
J. Exp. Bot.
68
2149-2162
2017
-
-
1
-
-
-
1
-
-
-
-
-
-
4
-
-
1
-
-
1
-
-
4
1
2
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
1
-
1
-
-
4
1
-
-
-
-
-
-
-
-
-
2
2
-
-
-
742600
Tavladoraki
Copper-containing amine oxida ...
Arabidopsis thaliana
Front. Plant Sci.
7
824
2016
-
-
-
-
-
-
1
-
2
1
-
4
-
1
-
-
-
-
-
-
-
-
4
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
2
1
-
4
-
-
-
-
-
-
-
-
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
743371
Zhang
-
Characterization of the coppe ...
Trifolium pratense
Nucl. Sci. Tech.
27
69
2016
-
-
-
-
-
-
-
8
-
-
-
-
-
1
-
-
1
-
-
1
-
-
9
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
8
-
-
-
-
-
-
-
1
-
1
-
-
9
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
742606
Huang
-
Copper amine oxidase-catalyse ...
Vicia faba
Funct. Plant Biol.
42
1057-1067
2015
-
-
-
-
-
-
2
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
1
-
-
-
742881
Murakawa
probing the catalytic mechani ...
Arthrobacter globiformis
J. Biol. Chem.
290
23094-23109
2015
-
-
-
1
-
-
4
-
-
1
-
-
-
8
-
-
-
-
-
-
-
-
3
-
2
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
1
-
-
-
4
-
-
-
1
-
-
-
-
-
-
-
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Primary amine oxidase of Esch ...
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Synthesis of 2,6-disubstitute ...
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705350
Iffiu-Soltesz
Influence of prolonged fasting ...
Rattus norvegicus
J. Physiol. Biochem.
65
11-23
2009
1
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2
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2
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705496
Vavilova
Monoamine oxidase and semicarb ...
Homo sapiens
Med. Sci. Monit.
15
BR289-BR292
2009
-
-
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1
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1
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1
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1
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1
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-
-
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1
1
-
-
-
712188
Martelius
Inhibition of semicarbazide-se ...
Rattus norvegicus
Int. J. Immunopathol. Pharmacol.
21
911-920
2009
-
-
-
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1
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1
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1
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1
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1
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5
-
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1
1
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-
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1
1
-
-
-
684124
Dai
Synthetic liver X receptor ago ...
Mus musculus
Acta Biochim. Biophys. Sin. (Shanghai)
40
261-268
2008
-
-
-
-
-
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1
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1
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2
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686264
Dunkel
Semicarbazide-sensitive amine ...
Bos taurus, Homo sapiens, Mus musculus, Rattus norvegicus
Curr. Med. Chem.
15
1827-1839
2008
-
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45
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5
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3
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26
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4
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45
-
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45
45
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3
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26
-
-
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-
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-
686850
Lin
Antioxidant, anti-semicarbazid ...
Bos taurus
Food Chem. Toxicol.
46
2485-2492
2008
-
-
-
-
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1
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1
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1
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1
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1
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-
-
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-
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-
-
-
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-
-
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-
687077
Fracassini
Endogenous substrates of the s ...
Rattus norvegicus
Inflamm. Res.
57
S53-S54
2008
-
-
-
-
-
-
1
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1
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1
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1
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1
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1
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1
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1
-
-
-
-
-
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-
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-
-
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-
687307
Langley
Enantiomer-specific binding of ...
Arthrobacter globiformis
J. Am. Chem. Soc.
130
8069-8078
2008
-
-
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1
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1
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3
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1
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1
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1
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1
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-
-
-
-
-
-
-
-
687459
Lee
Purification and characterizat ...
Mycobacterium sp., Mycobacterium sp. DSM 3803 / JC1
J. Biochem.
144
107-114
2008
-
-
-
-
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6
2
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1
4
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6
-
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1
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1
2
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6
2
2
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1
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1
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1
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6
-
2
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1
4
-
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1
-
1
2
-
6
2
-
-
-
-
1
-
-
-
-
-
-
-
-
-
688002
Wiwanitkit
Synergistic interaction betwee ...
Homo sapiens
J. Diabetes Complicat.
22
413-419
2008
-
-
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-
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-
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1
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1
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1
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1
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1
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-
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-
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-
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-
688100
An
Hydrogen peroxide generated by ...
Vicia faba
J. Exp. Bot.
59
815-825
2008
-
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4
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1
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1
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-
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-
-
-
-
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-
688553
Sibon
Association between semicarbaz ...
Rattus norvegicus
J. Neurosurg.
108
558-566
2008
-
-
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1
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1
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1
-
-
-
-
-
-
-
-
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-
-
-
-
-
688603
ORourke
Anti-inflammatory effects of L ...
Homo sapiens, Mus musculus, Rattus norvegicus
J. Pharmacol. Exp. Ther.
324
867-875
2008
-
-
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3
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3
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3
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3
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3
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4
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4
3
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3
-
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3
-
-
-
-
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-
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-
-
-
-
-
-
-
-
689200
Jiang
The contribution of cerebral v ...
Homo sapiens
Neuropathol. Appl. Neurobiol.
34
194-204
2008
-
-
-
-
-
-
-
-
-
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1
-
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1
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1
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-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
689377
Carpene
Limitation of adipose tissue e ...
Rattus norvegicus
Pharmacol. Res.
57
426-434
2008
-
-
-
-
-
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2
-
-
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7
-
-
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4
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1
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2
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4
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
701483
Pirrat
Structure of a xenon derivativ ...
Escherichia coli
Acta Crystallogr. Sect. F
64
1105-1109
2008
-
-
-
1
-
-
-
-
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1
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4
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1
1
1
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1
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1
1
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1
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1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
701487
Atkin
Cloning, expression, purificat ...
Aspergillus niger
Acta Crystallogr. Sect. F
64
182-185
2008
-
-
1
1
3
-
2
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-
-
-
-
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1
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1
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1
1
1
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1
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1
1
1
3
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2
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1
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-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
701490
Langley
Complexes of the copper-contai ...
Arthrobacter globiformis
Acta Crystallogr. Sect. F
64
577-583
2008
-
-
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1
-
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2
-
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1
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4
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3
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1
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1
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1
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-
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-
-
-
-
-
-
-
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-
-
-
-
-
-
-
-
703506
Peter
Copper distributed by Atx1 is ...
no activity in Saccharomyces cerevisiae, Schizosaccharomyces pombe, Schizosaccharomyces pombe FY435 / ATCC 87284
Eukaryot. Cell
7
1781-1794
2008
2
-
1
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5
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1
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2
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6
-
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4
1
3
1
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1
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1
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2
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1
1
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5
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1
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2
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-
-
-
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4
1
1
-
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-
1
-
-
-
-
1
1
-
-
-
705128
Atkin
The structure of monoamine oxi ...
Aspergillus niger
J. Mol. Biol.
384
1218-1231
2008
-
-
1
1
2
-
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-
-
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1
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1
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1
1
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-
-
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1
1
1
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-
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1
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1
1
1
2
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1
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1
1
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-
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
684285
Gokturk
Macrovascular changes in mice ...
Homo sapiens
Am. J. Hypertens.
20
743-750
2007
-
-
1
-
-
-
-
-
-
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1
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1
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2
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2
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1
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1
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-
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2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
684685
Di Paolo
N-alkanamines as substrates to ...
Bos taurus
Arch. Biochem. Biophys.
465
50-60
2007
-
-
-
-
-
-
-
-
-
-
-
-
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5
-
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1
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2
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6
-
2
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-
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-
-
-
-
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-
-
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1
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2
-
-
6
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
685663
Wang
DPPH radical scavenging and se ...
Homo sapiens, Mus musculus
Biosci. Biotechnol. Biochem.
71
1873-1878
2007
-
-
-
-
-
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2
-
-
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-
-
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2
-
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-
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2
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2
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4
-
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-
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-
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-
-
-
-
-
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2
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2
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
686052
Yraola
Understanding the mechanism of ...
Homo sapiens, Mus musculus, Rattus norvegicus
Chem. Biol. Drug Des.
69
423-428
2007
-
3
-
-
-
-
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6
2
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-
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3
-
-
-
-
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2
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6
-
3
-
-
-
-
-
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3
-
-
-
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6
2
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-
-
2
-
-
6
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
686502
Roessner
Decreased serum activity of se ...
Homo sapiens
Eur. J. Clin. Pharmacol.
63
425-429
2007
-
-
-
-
-
-
-
-
-
-
-
-
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1
-
-
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-
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1
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1
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2
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-
-
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-
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-
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-
-
-
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-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
687276
Moore
Trapping of a dopaquinone inte ...
Arthrobacter globiformis
J. Am. Chem. Soc.
129
11524-11534
2007
-
-
-
1
2
-
-
-
-
1
-
-
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4
-
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1
-
-
-
-
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1
-
3
-
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-
-
-
-
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1
-
-
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-
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1
1
2
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-
-
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1
-
-
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1
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
687449
Hernandez-Guillamon
Sodium bicarbonate enhances me ...
Homo sapiens
J. Biochem.
142
571-576
2007
-
-
-
-
-
-
-
-
2
1
-
-
-
1
-
-
-
-
-
2
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1
-
2
-
-
-
-
-
-
-
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-
-
-
-
-
-
-
-
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-
2
1
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-
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2
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
688255
Leonetti
Solid-phase synthesis and insi ...
Homo sapiens
J. Med. Chem.
50
4909-4916
2007
-
-
-
-
-
-
1
-
-
-
-
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1
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-
-
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2
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1
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2
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-
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-
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1
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-
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2
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
688482
Olivieri
L-lysine as a recognition mole ...
Bos taurus
J. Neural Transm.
114
747-749
2007
-
-
-
-
-
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1
-
-
-
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1
-
1
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-
-
-
1
-
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2
-
2
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-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
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1
1
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-
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1
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-
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1
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
688483
O'Sullivan
Hydrogen peroxide derived from ...
Bos taurus
J. Neural Transm.
114
751-756
2007
-
-
-
-
-
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1
-
-
-
-
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1
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-
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1
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-
1
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2
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-
-
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688484
Yabanoglu
Interaction of rat lung SSAO w ...
Rattus norvegicus
J. Neural Transm.
114
769-773
2007
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8
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1
1
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688487
Bour
Semicarbazide-sensitive amine ...
Mus musculus
J. Neural Transm.
114
829-833
2007
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688488
Nemcsik
Alteration of serum semicarbaz ...
Homo sapiens
J. Neural Transm.
114
841-843
2007
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688489
Soltesz
Studies on the insulinomimetic ...
Rattus norvegicus
J. Neural Transm.
114
851-855
2007
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7
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688490
Unzeta
Semicarbazide-sensitive amine ...
Homo sapiens
J. Neural Transm.
114
857-862
2007
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688491
Vidrio
Hypotensive effect of hydroxyl ...
Rattus norvegicus
J. Neural Transm.
114
863-865
2007
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688757
Takahashi
Absence of tissue-bound semica ...
no activity in Cyprinus carpio
Life Sci.
80
1094-1099
2007
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689375
Carpene
Reduction of fat deposition by ...
Rattus norvegicus
Pharmacol. Res.
56
522-530
2007
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1
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689376
Prevot
Prolonged treatment with amino ...
Rattus norvegicus
Pharmacol. Res.
56
70-79
2007
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1
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1
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671747
Murakawa
Quantum mechanical hydrogen tu ...
Arthrobacter globiformis
Biochem. Biophys. Res. Commun.
342
414-423
2006
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1
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672133
DuBois
Role of a strictly conserved a ...
Ogataea angusta
Biochemistry
45
3178-3188
2006
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2
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6
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3
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3
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3
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3
-
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-
672146
Chiu
Kinetic and structural studies ...
Arthrobacter globiformis
Biochemistry
45
4105-4120
2006
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1
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2
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6
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1
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1
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2
-
1
-
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-
672152
Takahashi
Relationship of stopped flow t ...
Ogataea angusta
Biochemistry
45
4683-4694
2006
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2
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11
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1
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-
1
-
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-
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672492
Ochiai
Substrate selectivity of monoa ...
Rattus norvegicus
Biol. Pharm. Bull.
29
2362-2366
2006
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1
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9
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9
-
5
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671976
Okajima
Reinvestigation of metal ion s ...
Arthrobacter globiformis
Biochemistry
44
12041-12048
2005
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1
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3
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3
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1
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3
-
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675286
Bertini
Alkylamino derivatives of 4-am ...
Sus scrofa, Ogataea angusta, Pisum sativum
J. Med. Chem.
48
664-670
2005
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47
2
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8
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2
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6
-
6
-
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37
-
-
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37
47
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2
-
1
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2
-
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6
-
-
-
-
-
-
-
-
-
-
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676364
Longu
Mechanism-based inactivators o ...
Lens culinaris, Onobrychis viciifolia, Pisum sativum, Lathyrus sativus
Phytochemistry
66
1751-1758
2005
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38
3
-
4
-
-
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4
-
4
-
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2
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-
37
1
12
-
-
-
2
-
-
-
4
5
-
-
-
-
-
4
-
-
-
-
38
5
3
-
4
-
-
-
-
4
-
-
2
-
-
37
1
-
-
-
2
-
-
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-
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-
-
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655782
Kishishita
Role of copper ion in bacteria ...
Arthrobacter globiformis
J. Am. Chem. Soc.
125
1041-1055
2003
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1
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6
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3
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1
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1
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1
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6
-
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1
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6
-
3
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1
-
-
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1
-
-
-
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6
-
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654501
Saysell
Probing the catalytic mechanis ...
Escherichia coli
Biochem. J.
365
809-816
2002
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2
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1
11
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2
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1
-
1
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-
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11
-
-
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1
-
-
-
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-
1
-
2
-
-
1
-
11
-
1
-
-
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-
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2
-
1
-
-
-
-
11
-
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-
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654616
Mills
Mechanistic comparison of the ...
Ogataea angusta
Biochemistry
41
10577-10584
2002
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5
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1
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2
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1
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2
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1
-
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655781
Lee
3-Pyrrolines are mechanism-bas ...
Bos taurus
J. Am. Chem. Soc.
124
12135-12143
2002
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9
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3
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1
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2
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1
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1
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9
-
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1
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3
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1
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391960
Mills
-
Evidence against reduction of ...
Ogataea angusta, Ogataea angusta 1A2V
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122
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1
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6
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4
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2
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-
1
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2
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1
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1
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6
-
4
-
-
-
-
2
-
-
-
-
-
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-
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391956
Li
Copper amine oxidase from Hans ...
Ogataea angusta, Ogataea angusta 1A2V
Structure
6
293-307
1998
-
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-
1
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1
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8
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2
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-
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1
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1
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2
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-
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-
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391949
Cai
Copper amine oxidase: heterolo ...
Ogataea angusta, Ogataea angusta 1A2V
Biochemistry
33
7647-7653
1994
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1
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3
1
1
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9
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1
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1
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6
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1
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1
1
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3
1
1
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1
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1
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6
-
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391937
Hysmith
Purification of benzylamine ox ...
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Biochem. Cell Biol.
66
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1988
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5
1
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1
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3
1
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2
1
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-
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-
-
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5
-
1
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1
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1
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3
1
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2
1
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391914
Falk
Heterogeneity of pig plasma am ...
Sus scrofa
Biochemistry
22
3746-3751
1983
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1
1
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1
2
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4
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1
1
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3
1
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2
1
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1
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1
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1
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1
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1
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1
2
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1
1
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3
1
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2
1
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1
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391932
Barker
Properties of cupric ions in b ...
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Biochem. J.
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3
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1
1
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5
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3
5
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1
2
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3
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1
1
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391910
Carper
-
Pig liver monoamine oxidase I: ...
Sus scrofa
Biochim. Biophys. Acta
334
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1974
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1
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1
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1
1
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1
1
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1
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5
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2
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5
2
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1
1
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2
1
1
1
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1
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391915
Lindström
Effect of azide on some spectr ...
Sus scrofa
Eur. J. Biochem.
48
237-243
1974
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4
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1
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1
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1
1
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1
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4
1
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1
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1
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1
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391916
Lindström
Kinetics of the interaction be ...
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Eur. J. Biochem.
42
177-182
1974
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1
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1
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391908
Yamada
Monoamine oxidase II. Copper, ...
Bos taurus
J. Biol. Chem.
237
3077-3082
1962
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