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Literature summary for 1.4.3.2 extracted from

  • Pajak, M.
    Methylated derivatives of L-tyrosine in reaction catalyzed by L-amino acid oxidase isotope and inhibitory effects (2020), J. Biochem., 168, 509-514 .
    View publication on PubMed
Search for more literature for 1.4.3.2

Inhibitors

Inhibitors Comment Organism Structure
alpha-methyl-L-tyrosine mixed type inhibitor Crotalus atrox
N-methyl-L-tyrosine competitive inhibitor Crotalus atrox

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.044
-
 O-methyl-L-tyrosine pH 7.5, temperature not specified in the publication Crotalus atrox
0.13
-
 L-tyrosine pH 7.5, temperature not specified in the publication Crotalus atrox
0.19
-
 L-tyrosine presence of 1 mM O-methyl-L-tyrosine, pH 7.5, temperature not specified in the publication Crotalus atrox

Organism

Organism UniProt Comment Textmining
Crotalus atrox P56742
-
-

Source Tissue

Source Tissue Comment Organism Textmining
commercial preparation
-
 Crotalus atrox
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-tyrosine + H2O + O2
-
 Crotalus atrox 3-(4-hydroxyphenyl)-2-oxopropanoate + NH3 + H2O2
-
 ?
O-methyl-L-tyrosine + H2O + O2
-
 Crotalus atrox 3-(4-methoxyphenyl)-2-oxopropanoate + NH3 + H2O2
-
 ?

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
3.12
-
 alpha-methyl-L-tyrosine pH 7.5, temperature not specified in the publication Crotalus atrox
7.96
-
 N-methyl-L-tyrosine pH 7.5, temperature not specified in the publication Crotalus atrox