Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
extracellular | - |
Bothrops jararaca | - |
- |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-leucine + H2O + O2 | Bothrops jararaca | - |
2-oxo-4-methylvaleric acid + NH3 + H2O2 | - |
? | |
additional information | Bothrops jararaca | Bothrops jararaca venom induces programmed cell death in epimastigotes of Trypanosoma cruzi due to its L-AAO activity, L-AAO activity induces parasites cytoplasmic retraction, mitochondrial swelling and DNA fragmentation, overview. L-AAO produces H2O2, which is highly toxic | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bothrops jararaca | - |
- |
- |
Purification (Comment) | Organism |
---|---|
native extracellular enzyme from venom by gel filtration and anion exchange chromatography | Bothrops jararaca |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
venom | - |
Bothrops jararaca | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-leucine + H2O + O2 | - |
Bothrops jararaca | 2-oxo-4-methylvaleric acid + NH3 + H2O2 | - |
? | |
additional information | Bothrops jararaca venom induces programmed cell death in epimastigotes of Trypanosoma cruzi due to its L-AAO activity, L-AAO activity induces parasites cytoplasmic retraction, mitochondrial swelling and DNA fragmentation, overview. L-AAO produces H2O2, which is highly toxic | Bothrops jararaca | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
L-AAO | - |
Bothrops jararaca |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
25 | - |
assay at | Bothrops jararaca |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8.5 | - |
assay at | Bothrops jararaca |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
FAD | - |
Bothrops jararaca |