Application | Comment | Organism |
---|---|---|
additional information | LAAO causes cell death by induction of apoptosis in yeast. Lower concentrations of hydrogen peroxide accompanied by leucine deficiency may have a role in enhancing cell death in leucine auxotrophic yeast strain. LAAO interacts with the cell surface of yeast. Depletion of leucine from the medium by LAAO and the interaction of LAAO with yeast cells are shown to be the major factors responsible for cell demise in the presence of catalase | Calloselasma rhodostoma |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | catalase (1.5 micromol) at various concentrations of leucine does not completely inhibit cell death caused by LAAO (1.2 micromol) in leucine auxotrophic strain | Calloselasma rhodostoma |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Calloselasma rhodostoma | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
venom | - |
Calloselasma rhodostoma | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-leucine + H2O + O2 | - |
Calloselasma rhodostoma | 4-methyl-2-oxopentanoic acid + NH3 + H2O2 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
LAAO | - |
Calloselasma rhodostoma |