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Literature summary for 1.4.3.2 extracted from

  • Du, X.Y.; Clemetson, K.J.
    Snake venom L-amino acid oxidases (2002), Toxicon, 40, 659-665.
    View publication on PubMed

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
56000
-
2 * 56000 Pseudechis australis
57400
-
2 * 57400 Naja kaouthia
58700
-
2 * 58700 Crotalus adamanteus
60000
-
2 * 60000 Agkistrodon contortrix laticinctus
65000
-
2 * 65000 Ophiophagus hannah
66000
-
2 * 66000 Calloselasma rhodostoma
66000
-
2 * 66000 Eristicophis macmahoni
69000
-
2 * 69000 Bothrops moojeni
69000
-
2 * 69000 Crotalus atrox
70000
-
2 * 70000 Protobothrops mucrosquamatus
112000
-
-
Naja kaouthia
120000
-
-
Agkistrodon contortrix laticinctus
132000
-
-
Calloselasma rhodostoma
132000
-
-
Eristicophis macmahoni
135000
-
-
Ophiophagus hannah
140000
-
-
Bothrops moojeni
140000
-
-
Crotalus atrox
140000
-
-
Protobothrops mucrosquamatus
142000
-
-
Pseudechis australis

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-amino acid + H2O + O2 snake biological functions of snake venom enzymes 2-oxo acid + NH3 + H2O2
-
?
additional information Protobothrops flavoviridis induces apoptosis ?
-
?
additional information Protobothrops mucrosquamatus induces apoptosis ?
-
?
additional information Eristicophis macmahoni induces apoptosis ?
-
?
additional information Gloydius blomhoffii induction of apoptosis ?
-
?
additional information Agkistrodon contortrix laticinctus induction of apoptosis ?
-
?

Organism

Organism UniProt Comment Textmining
Agkistrodon contortrix laticinctus
-
-
-
Bothrops moojeni
-
-
-
Calloselasma rhodostoma
-
-
-
Crotalus adamanteus
-
-
-
Crotalus atrox
-
-
-
Eristicophis macmahoni
-
-
-
Gloydius blomhoffii
-
-
-
Naja kaouthia
-
-
-
Ophiophagus hannah
-
-
-
Protobothrops flavoviridis
-
-
-
Protobothrops mucrosquamatus
-
-
-
Pseudechis australis
-
-
-
snake
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
glycoprotein
-
Crotalus adamanteus
glycoprotein
-
Ophiophagus hannah

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
enzyme assays snake

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-amino acid + H2O + O2
-
snake 2-oxo acid + NH3 + H2O2
-
?
L-amino acid + H2O + O2 biological functions of snake venom enzymes snake 2-oxo acid + NH3 + H2O2
-
?
additional information enzymatic properties of snake venom enzymes, mechanisms of enzyme-induced platelet aggregation and apoptosis snake ?
-
?
additional information induces apoptosis Protobothrops flavoviridis ?
-
?
additional information induces apoptosis Protobothrops mucrosquamatus ?
-
?
additional information induces apoptosis Eristicophis macmahoni ?
-
?
additional information induction of apoptosis Gloydius blomhoffii ?
-
?
additional information induction of apoptosis Agkistrodon contortrix laticinctus ?
-
?
additional information induces platelet aggregation Ophiophagus hannah ?
-
?
additional information induces platelet aggregation Eristicophis macmahoni ?
-
?
additional information inhibits aggregation of platelets Gloydius blomhoffii ?
-
?
additional information inhibits platelet aggregation Naja kaouthia ?
-
?

Subunits

Subunits Comment Organism
dimer 2 * 56000 Pseudechis australis
dimer 2 * 69000 Bothrops moojeni
dimer 2 * 69000 Crotalus atrox
dimer 2 * 70000 Protobothrops mucrosquamatus
dimer 2 * 60000 Agkistrodon contortrix laticinctus
dimer 2 * 57400 Naja kaouthia
dimer 2 * 58700 Crotalus adamanteus
dimer 2 * 65000 Ophiophagus hannah
dimer 2 * 66000 Calloselasma rhodostoma
dimer 2 * 66000 Eristicophis macmahoni
More overview on structural properties snake

pI Value

Organism Comment pI Value Maximum pI Value
Calloselasma rhodostoma
-
-
4.2
Eristicophis macmahoni
-
-
4.2
Agkistrodon contortrix laticinctus
-
-
4.2
Bothrops moojeni
-
-
4.9
Ophiophagus hannah
-
-
4.9
Gloydius blomhoffii
-
-
4.9
Naja kaouthia
-
-
6.9