BRENDA - Enzyme Database
show all sequences of 1.4.3.15

Physiological role of D-aspartate oxidase in the assimilation and detoxification of D-aspartate in the yeast Cryptococcus humicola

Takahashi, S.; Kakuichi, T.; Fujii, K.; Kera, Y.; Yamada, R.; Yeast 22, 1203-1212 (2005)

Data extracted from this reference:

Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
D-aspartic acid + H2O + O2
Vanrija humicola
DASPO plays an essential role in the assimilation of D-aspartate and acts as a detoxifying agent for D-aspartate
oxaloacetate + NH3 + H2O2
-
-
?
D-glutamic acid + H2O + O2
Vanrija humicola
enzyme is also involved in the detoxification of D-glutamate, although enzyme induction by this amino acid is very limited
2-oxoglutarate + NH3 + H2O2
-
-
?
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Vanrija humicola
-
-
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
D-aspartic acid + H2O + O2
-
677271
Vanrija humicola
oxaloacetate + NH3 + H2O2
-
-
-
?
D-aspartic acid + H2O + O2
DASPO plays an essential role in the assimilation of D-aspartate and acts as a detoxifying agent for D-aspartate
677271
Vanrija humicola
oxaloacetate + NH3 + H2O2
-
-
-
?
D-glutamic acid + H2O + O2
-
677271
Vanrija humicola
2-oxoglutarate + NH3 + H2O2
-
-
-
?
D-glutamic acid + H2O + O2
enzyme is also involved in the detoxification of D-glutamate, although enzyme induction by this amino acid is very limited
677271
Vanrija humicola
2-oxoglutarate + NH3 + H2O2
-
-
-
?
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
D-aspartic acid + H2O + O2
Vanrija humicola
DASPO plays an essential role in the assimilation of D-aspartate and acts as a detoxifying agent for D-aspartate
oxaloacetate + NH3 + H2O2
-
-
?
D-glutamic acid + H2O + O2
Vanrija humicola
enzyme is also involved in the detoxification of D-glutamate, although enzyme induction by this amino acid is very limited
2-oxoglutarate + NH3 + H2O2
-
-
?
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
D-aspartic acid + H2O + O2
-
677271
Vanrija humicola
oxaloacetate + NH3 + H2O2
-
-
-
?
D-aspartic acid + H2O + O2
DASPO plays an essential role in the assimilation of D-aspartate and acts as a detoxifying agent for D-aspartate
677271
Vanrija humicola
oxaloacetate + NH3 + H2O2
-
-
-
?
D-glutamic acid + H2O + O2
-
677271
Vanrija humicola
2-oxoglutarate + NH3 + H2O2
-
-
-
?
D-glutamic acid + H2O + O2
enzyme is also involved in the detoxification of D-glutamate, although enzyme induction by this amino acid is very limited
677271
Vanrija humicola
2-oxoglutarate + NH3 + H2O2
-
-
-
?
Other publictions for EC 1.4.3.15
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
677271
Takahashi
Physiological role of D-aspart ...
Vanrija humicola
Yeast
22
1203-1212
2005
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391755
Onishi
Mutants of Neurospora deficien ...
Neurospora crassa
J. Biol. Chem.
237
138-142
1962
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391754
Mitzushima
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Studies on the metabolism of D ...
Aspergillus ustus
J. Gen. Appl. Microbiol.
3
233-239
1957
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