Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
nucleus | - |
Mus musculus | 5634 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
peptide acK685 + O2 + H2O | - |
Mus musculus | ? + NH3 + H2O2 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
LOX-like 3 | - |
Mus musculus |
Loxl3 | - |
Mus musculus |
lysyl oxidase 3 | - |
Mus musculus |
General Information | Comment | Organism |
---|---|---|
metabolism | by deacetylating and deacetyliminating Stat3 on multiple acetyl-lysine sites in nuclei, the enzyme regulates Stat3 dimerization and transcriptional activity. Furthermore, CD4+ T cell differentiation in inflammatory responses is regulated by the enzyme-Stat3 signaling pathway | Mus musculus |
physiological function | the enzyme restricts Stat3-dependent cell proliferation and immune cell differentiation and inflammatory response | Mus musculus |