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Literature summary for 1.4.3.13 extracted from

  • Kim, D.J.; Lee, D.C.; Yang, S.J.; Lee, J.J.; Bae, E.M.; Kim, D.M.; Min, S.H.; Kim, S.J.; Kang, D.C.; Sang, B.C.; Myung, P.K.; Park, K.C.; Yeom, Y.I.
    Lysyl oxidase like 4, a novel target gene of TGF-beta1 signaling, can negatively regulate TGF-beta1-induced cell motility in PLC/PRF/5 hepatoma cells (2008), Biochem. Biophys. Res. Commun., 373, 521-527.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
transforming growth factor-beta1 2 ng/ml upregulates LOXL4 expression Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
additional information LOXL4 suppresses the expression of laminins and alpha3 integrin and the activity of matrix metalloproteinase-2 Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
Hep-G2 cell
-
Homo sapiens
-
hepatoma cell
-
Homo sapiens
-
PLC/PRF/5 cell
-
Homo sapiens
-
SNU-182 cell
-
Homo sapiens
-

Synonyms

Synonyms Comment Organism
LOXL4
-
Homo sapiens
lysyl oxidase like 4
-
Homo sapiens