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Literature summary for 1.4.1.4 extracted from

  • Amin, A.; Joshi, M.; Deshpande, M.V.
    Morphology-associated expression of NADP-dependent glutamate dehydrogenases during yeast-mycelium transition of a dimorphic fungus Benjaminiella poitrasii (2004), Antonie van Leeuwenhoek, 85, 327-334.
    View publication on PubMed
Search for more literature for 1.4.1.4

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Benjaminiella poitrasii the yeast form specific isoenzyme is induced in presence of glucose, the mycelium-form is not induced. Possible involvement of the enzyme in yeast-mycelium transition ?
-
 ?

Organism

Organism UniProt Comment Textmining
Benjaminiella poitrasii
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
phosphoprotein phosphorylation increases the activity of the mycelial form of the enzyme. The yeast enzyme remains unaffected. The yeast-form specific native NADP-GDH is in active phosphorylated form. In mycelium the native enzyme is in dephosphorylated inactive form Benjaminiella poitrasii

Source Tissue

Source Tissue Comment Organism Textmining
mycelium two different enzymes in yeast and in mycelium cells Benjaminiella poitrasii
-
yeast form two different enzymes in yeast and in mycelium cells Benjaminiella poitrasii
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-oxoglutarate + NADPH + NH3
-
 Benjaminiella poitrasii L-glutamate + NADP+ + H2O
-
 ?
additional information the yeast form specific isoenzyme is induced in presence of glucose, the mycelium-form is not induced. Possible involvement of the enzyme in yeast-mycelium transition Benjaminiella poitrasii ?
-
 ?

Synonyms

Synonyms Comment Organism
NADP-dependent glutamate dehydrogenase 2 isoenzymes: a yeast-form isoenzyme and a mycelium-form isoenzyme Benjaminiella poitrasii

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
28
-
 enzyme from mycelium Benjaminiella poitrasii
32
-
 enzyme from yeast Benjaminiella poitrasii

Temperature Stability [°C]

Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
37
-
 60 min, yeast enzyme retains 41% of its activity, mycelial enzyme retains 9% of its activity Benjaminiella poitrasii

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7
-
 enzyme from mycelium and yeast Benjaminiella poitrasii

Cofactor

Cofactor Comment Organism Structure
NADPH
-
 Benjaminiella poitrasii