Cloned (Comment) | Organism |
---|---|
expression in Sf9 cells | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
17beta-estradiol | - |
Homo sapiens | |
corticosterone | - |
Homo sapiens | |
dehydroepiandrosterone | - |
Homo sapiens | |
dehydrotestosterone | - |
Homo sapiens | |
diethylstilbestrol | - |
Homo sapiens | |
estriol | - |
Homo sapiens | |
pregnenolone | - |
Homo sapiens | |
progesterone | - |
Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P00367 | - |
- |
Homo sapiens | P49448 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
adrenal | dense expression of both isoforms Gdh1 and Gdh2 | Homo sapiens | - |
brain | expression of both isoforms Gdh1 and Gdh2 | Homo sapiens | - |
kidney | expression of both isoforms Gdh1 and Gdh2 | Homo sapiens | - |
liver | high expression of isoform Gdh1 | Homo sapiens | - |
additional information | no expression in hepaocyte | Homo sapiens | - |
additional information | no expression in Sertoli cells | Homo sapiens | - |
ovary | both hGDH1 and hGDH2 are densely expressed in estrogen producing cells | Homo sapiens | - |
placenta | both hGDH1 and hGDH2 are densely expressed in estrogen producing cells | Homo sapiens | - |
Sertoli cell | strong expression 0f isoform Gdh2 | Homo sapiens | - |
testis | expression of both isoforms Gdh1 and Gdh2 | Homo sapiens | - |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.001 | - |
pH 8.0, temperature not specified in the publication | Homo sapiens | corticosterone | |
0.001 | - |
presence of 0.1 M ADP, pH 8.0, temperature not specified in the publication | Homo sapiens | diethylstilbestrol | |
0.0015 | - |
pH 8.0, temperature not specified in the publication | Homo sapiens | 17beta-estradiol | |
0.00167 | - |
pH 8.0, temperature not specified in the publication | Homo sapiens | diethylstilbestrol | |
0.0021 | - |
pH 8.0, temperature not specified in the publication | Homo sapiens | corticosterone | |
0.0025 | - |
presence of 0.1 M ADP, pH 8.0, temperature not specified in the publication | Homo sapiens | corticosterone | |
0.0032 | - |
presence of 0.1 M ADP, pH 8.0, temperature not specified in the publication | Homo sapiens | corticosterone | |
0.0071 | - |
presence of 0.1 M ADP, pH 8.0, temperature not specified in the publication | Homo sapiens | diethylstilbestrol | |
0.0072 | - |
pH 8.0, temperature not specified in the publication | Homo sapiens | dehydroepiandrosterone | |
0.008 | - |
pH 8.0, temperature not specified in the publication | Homo sapiens | diethylstilbestrol | |
0.0113 | - |
pH 8.0, temperature not specified in the publication | Homo sapiens | estriol | |
0.0117 | - |
pH 8.0, temperature not specified in the publication | Homo sapiens | pregnenolone | |
0.0123 | - |
pH 8.0, temperature not specified in the publication | Homo sapiens | progesterone | |
0.0151 | - |
presence of 0.1 M ADP, pH 8.0, temperature not specified in the publication | Homo sapiens | 17beta-estradiol | |
0.0269 | - |
pH 8.0, temperature not specified in the publication | Homo sapiens | 17beta-estradiol | |
0.0294 | - |
presence of 0.1 M ADP, pH 8.0, temperature not specified in the publication | Homo sapiens | dehydroepiandrosterone | |
0.0494 | - |
pH 8.0, temperature not specified in the publication | Homo sapiens | dehydrotestosterone | |
0.0541 | - |
presence of 0.1 M ADP, pH 8.0, temperature not specified in the publication | Homo sapiens | pregnenolone | |
0.0589 | - |
presence of 0.1 M ADP, pH 8.0, temperature not specified in the publication | Homo sapiens | progesterone | |
0.0692 | - |
presence of 0.1 M ADP, pH 8.0, temperature not specified in the publication | Homo sapiens | 17beta-estradiol | |
0.0915 | - |
presence of 0.1 M ADP, pH 8.0, temperature not specified in the publication | Homo sapiens | dehydrotestosterone | |
0.104 | - |
pH 8.0, temperature not specified in the publication | Homo sapiens | pregnenolone | |
0.119 | - |
pH 8.0, temperature not specified in the publication | Homo sapiens | progesterone | |
0.145 | - |
pH 8.0, temperature not specified in the publication | Homo sapiens | estriol | |
0.189 | - |
presence of 0.1 M ADP, pH 8.0, temperature not specified in the publication | Homo sapiens | estriol | |
0.216 | - |
pH 8.0, temperature not specified in the publication | Homo sapiens | dehydroepiandrosterone | |
0.287 | - |
presence of 0.1 M ADP, pH 8.0, temperature not specified in the publication | Homo sapiens | pregnenolone | |
0.316 | - |
presence of 0.1 M ADP, pH 8.0, temperature not specified in the publication | Homo sapiens | estriol | |
0.396 | - |
presence of 0.1 M ADP, pH 8.0, temperature not specified in the publication | Homo sapiens | dehydroepiandrosterone | |
0.494 | - |
pH 8.0, temperature not specified in the publication | Homo sapiens | dehydrotestosterone | |
0.596 | - |
presence of 0.1 M ADP, pH 8.0, temperature not specified in the publication | Homo sapiens | progesterone | |
0.814 | - |
presence of 0.1 M ADP, pH 8.0, temperature not specified in the publication | Homo sapiens | dehydrotestosterone |