Literature summary for 1.4.1.2 extracted from

Kim, H.; Kim, W.H.; Kim, M.; Jeong, S.H.; Lee, K.
Evaluation of a rapid membrane enzyme immunoassay for the simultaneous detection of glutamate dehydrogenase and toxin for the diagnosis of Clostridium difficile infection (2014), Ann. Lab. Med., 34, 235-239.

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Application

Application	Comment	Organism
medicine	evaluation of comercially available rapid membrane enzyme immunoassays that use either glutamate dehydrogenase antigen or toxin A and B detection or a combination of both. Sensitivity, specificity, positive predictive values, and negative predictive values are 63.6%, 98.0%, 76.1%, and 96.4%, respectively, for the CD COMPLETE-toxin assay and 75.5%, 97.4%, 72.5%, and 97.8%, respectively, for the VIDAS CDAB assay. In comparison to the enriched Clostridium difficile cultures, the sensitivity, specificity, positive predictive values, and negative predictive values for the CD COMPLETE-GDH assay are 91.0%, 92.4%, 70.5%, and 98.1%, respectively. The CD COMPLETE assay is a reliable method for the diagnosis of Costridium difficile infection and provides greater sensitivity than toxin enzyme immunoassay alone	Clostridioides difficile

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining

Organism

Organism	UniProt	Comment	Textmining
Clostridioides difficile	-	-	-

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Release 2023.1 (January 2023)