Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.4.1.12 extracted from

  • Somack, R.; Costilow, R.N.
    2,4-Diaminopentanoic acid C4 dehydrogenase, purification and properties of the protein (1973), J. Biol. Chem., 247, 385-388.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
5,5'-dithiobis(2-nitrobenzoate)
-
Acetoanaerobium sticklandii
iodoacetate
-
Acetoanaerobium sticklandii
N-ethylmaleimide
-
Acetoanaerobium sticklandii
p-chloromercuribenzoate
-
Acetoanaerobium sticklandii

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
35400
-
2 * 35400 SDS-PAGE, sedimentation centrifugation in 6 M guanidine-HCl Acetoanaerobium sticklandii
40000
-
2 * 40000 SDS-PAGE, gel electrophoresis Acetoanaerobium sticklandii
72000 80000 sedimentation equilibrium centrifugation Acetoanaerobium sticklandii
80000
-
gel electrophoresis Acetoanaerobium sticklandii

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2,4-diaminopentanoate + H2O + NAD(P)+ Acetoanaerobium sticklandii
-
2-amino-4-oxopentanoate + NH3 + NAD(P)H
-
?

Organism

Organism UniProt Comment Textmining
Acetoanaerobium sticklandii
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Acetoanaerobium sticklandii

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
272.5
-
-
Acetoanaerobium sticklandii

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2,4-diaminopentanoate + H2O + NAD(P)+
-
Acetoanaerobium sticklandii 2-amino-4-oxopentanoate + NH3 + NAD(P)H
-
?

Subunits

Subunits Comment Organism
dimer 2 * 35400 SDS-PAGE, sedimentation centrifugation in 6 M guanidine-HCl Acetoanaerobium sticklandii
dimer 2 * 40000 SDS-PAGE, gel electrophoresis Acetoanaerobium sticklandii

Cofactor

Cofactor Comment Organism Structure
NAD+
-
Acetoanaerobium sticklandii
NADP+
-
Acetoanaerobium sticklandii