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Literature summary for 1.4.1.1 extracted from
- Isotopic effects in mechanistic studies of biotransformations of fluorine derivatives of L-alanine catalysed by L-alanine dehydrogenase (2017), Appl. Radiat. Isot., 123, 21-25 .
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bacillus subtilis | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| commercial preparation | - |
Bacillus subtilis | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 3-fluoropyruvate + NH3 + NADH + H+ | - |
Bacillus subtilis | 3-fluoro-L-alanine + H2O + NAD+ | - |
? |  |
| additional information | transfer of hydride is a partially limiting step and the reaction rate is limited by the release of product NADH. The fluorine constituent doesn't cause a significant change in the area of bonds that are being converted, and deuteriated solvent present in the reaction medium only slightly affects the conversion of [E-S] complex into [E-P] complex | Bacillus subtilis | ? | - |
? | |
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Release 2023.1 (January 2023)
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