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Literature summary for 1.3.99.5 extracted from

  • Kim, J.; Lee, J.; Yoon, H.; Kim, Y.; Jun, W.; Hwang, K.; Cha, M.; Lee, Y.
    Inhibitory effect of curcuma longa L. extracts on 5-alpha reductase II activity (2014), J. Korean Soc. Food Sci. Nutr., 43, 318-322.
No PubMed abstract available
Search for more literature for 1.3.99.5

Inhibitors

Inhibitors Comment Organism Structure
additional information hot water extract and 20% (v/v) ethanol extract of Curcuma longa significantly inhibit 5-alpha reductase activity Homo sapiens
additional information hot water extract and 20% (v/v) ethanol extract of Curcuma longa significantly inhibit 5-alpha reductase activity Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
testosterone + reduced acceptor Homo sapiens
-
 5alpha-dihydrotestosterone + acceptor
-
 ?
testosterone + reduced acceptor Rattus norvegicus
-
 5alpha-dihydrotestosterone + acceptor
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
LNCaP cell
-
 Homo sapiens
-
prostate cancer cell
-
 Homo sapiens
-
prostate cancer cell
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
testosterone + reduced acceptor
-
 Homo sapiens 5alpha-dihydrotestosterone + acceptor
-
 ?
testosterone + reduced acceptor
-
 Rattus norvegicus 5alpha-dihydrotestosterone + acceptor
-
 ?

Synonyms

Synonyms Comment Organism
5-alpha reductase II
-
 Homo sapiens
5-alpha reductase II
-
 Rattus norvegicus