BRENDA - Reference to 1.3.99.5; Id = 711736

linolenic acid

strong inhibition

Rattus norvegicus

Monolinolein

strong inhibition

Rattus norvegicus

additional information

screening of biologically active constituents from Brassica rapa pollen in supercritical CO2 fluid extract, overview. No inhibition by 24-methylenecholesterol linolenate, cycloeucalenol linolenate, 24-methylenecholesterol palmitate, cycloeucalenol, pollinastanol, 24-methylenecholesterol, palmitic acid, and monopalmitin

Rattus norvegicus

microsome

-

Rattus norvegicus

-

dihydrotestosterone + NADP+

Rattus norvegicus

the enzyme performs conversion of testosterone to dihydrotestosterone

testosterone + NADPH + H+

-

r

Rattus norvegicus

-

liver

-

Rattus norvegicus

-

dihydrotestosterone + NADP+

-

711736

Rattus norvegicus

testosterone + NADPH + H+

-

r

dihydrotestosterone + NADP+

the enzyme performs conversion of testosterone to dihydrotestosterone

711736

Rattus norvegicus

testosterone + NADPH + H+

-

r

linolenic acid

strong inhibition

Rattus norvegicus

Monolinolein

strong inhibition

Rattus norvegicus

additional information

screening of biologically active constituents from Brassica rapa pollen in supercritical CO2 fluid extract, overview. No inhibition by 24-methylenecholesterol linolenate, cycloeucalenol linolenate, 24-methylenecholesterol palmitate, cycloeucalenol, pollinastanol, 24-methylenecholesterol, palmitic acid, and monopalmitin

Rattus norvegicus

microsome

-

Rattus norvegicus

-

dihydrotestosterone + NADP+

Rattus norvegicus

the enzyme performs conversion of testosterone to dihydrotestosterone

testosterone + NADPH + H+

-

r

liver

-

Rattus norvegicus

-

dihydrotestosterone + NADP+

-

711736

Rattus norvegicus

testosterone + NADPH + H+

-

r

dihydrotestosterone + NADP+

the enzyme performs conversion of testosterone to dihydrotestosterone

711736

Rattus norvegicus

testosterone + NADPH + H+

-

r

740834

Kim

-

Inhibitory effect of curcuma l ...

Homo sapiens, Rattus norvegicus

J. Korean Soc. Food Sci. Nutr.

43

318-322

2014

-

2

-

2

-

2

-

3

-

2

-

2

-

2

-

2

-

3

-

2

-

740982

Li

Steroid 5-alpha-reductase type ...

Homo sapiens

Mol. Biol. Rep.

40

3597-3608

2013

-

2

-

1

-

1

-

1

-

1

-

2

-

2

-

1

-

1

-

1

-

725483

van Oosterwijk

Structure and catalytic mechan ...

Rhodococcus jostii

J. Biol. Chem.

287

30975-30983

2012

-

1

7

-

3

-

1

-

1

-

3

-

1

-

1

7

-

3

-

1

-

3

-

3

710704

Szécsi

Determination of rat 5alpha-re ...

Rattus norvegicus

Acta Biol. Hung.

61

274-281

2010

-

7

-

2

-

1

-

1

-

2

-

7

-

7

-

1

-

1

-

712093

Cohen

Testosterone selectively affec ...

Anolis carolinensis

Gen. Comp. Endocrinol.

166

128-133

2010

1

-

2

-

2

-

2

-

4

-

1

-

1

-

2

-

2

-

4

-

1

-

712094

Ramos

Cloning and differential expre ...

Mesocricetus auratus

Gen. Comp. Endocrinol.

166

388-395

2010

-

1

-

1

-

1

-

3

-

3

-

2

-

4

-

2

-

2

-

2

-

1

-

1

-

4

-

2

-

2

-

1

2

1

-

712095

Langlois

Evolution of steroid-5alpha-re ...

Canis lupus familiaris, Danio rerio, Gallus gallus, Homo sapiens, Mus musculus, Rattus norvegicus, Xenopus tropicalis

Gen. Comp. Endocrinol.

166

489-497

2010

-

7

-

23

1

-

8

-

4

-

14

-

3

-

7

-

23

-

1

-

4

-

3

-

7

-

712124

Ko

Clinical characterization and ...

Homo sapiens

Horm. Res. Paediatr.

73

41-48

2010

-

1

-

3

-

2

-

1

-

1

-

1

-

3

-

1

-

1

-

712125

Walter

Difficulties in diagnosis and ...

Homo sapiens

Horm. Res. Paediatr.

74

67-71

2010

-

1

-

1

-

1

-

2

-

1

-

1

-

2

-

713449

Gupta

Inhibition of 5alpha-reductase ...

Homo sapiens

Prostate

70

1575-1585

2010

-

2

-

4

-

2

-

1

-

2

-

2

-

1

-

713519

Aggarwal

An overview on 5alpha-reductas ...

Homo sapiens, Rattus norvegicus

Steroids

75

109-153

2010

-

417

-

2

-

2

-

4

-

9

-

4

-

8

-

2

27

-

347

-

4

-

403

740

32

-

3

-

2

-

10

-

4

-

1

2

-

713520

Aggarwal

Self-organizing molecular fiel ...

Homo sapiens

Steroids

75

411-418

2010

-

31

2

1

-

1

-

2

-

2

-

2

-

2

-

2

-

30

-

2

-

30

31

-

2

1

-

1

-

2

-

2

-

713595

Wang

Establishment of a novel model ...

Homo sapiens

Yakugaku Zasshi

130

1207-1214

2010

-

1

-

5

1

-

1

-

2

-

1

-

2

-

3

1

-

1

-

1

-

1

-

1

5

-

1

-

1

-

1

-

2

-

1

-

1

-

1

-

711658

Paz-y-Min

Association among polymorphism ...

Homo sapiens

Cancer Genet. Cytogenet.

189

71-76

2009

-

1

-

2

-

2

-

1

-

1

-

2

-

711736

Li

5 alpha-reductase and aromatas ...

Rattus norvegicus

Chem. Pharm. Bull.

57

401-404

2009

-

3

-

1

-

1

-

1

-

1

-

2

-

3

-

1

-

1

-

1

-

2

-

711937

Seo

Regulation of steroid 5-alpha ...

Mus musculus

Exp. Cell Res.

315

3133-3139

2009

-

1

-

1

-

3

-

3

-

2

-

1

-

1

-

3

-

1

2

1

-

713080

Kim

Synthesis of pregnane derivati ...

Homo sapiens

Molecules

14

4655-4668

2009

-

16

-

1

-

1

-

3

-

2

-

3

1

-

1

-

16

-

1

-

3

-

2

-

1

-

1

-

713447

Thomas

Overexpression of 5alpha-reduc ...

Homo sapiens

Prostate

69

595-602

2009

-

1

-

2

-

2

-

1

-

4

-

1

-

1

-

3

-

2

-

2

-

2

4

-

687319

Baldinotti

Molecular characterization of ...

Homo sapiens

J. Androl.

29

20-28

2008

-

6

-

2

-

2

-

2

-

6

-

2

-

688720

Amory

The effect of 5alpha-reductase ...

Homo sapiens

J. Urol.

179

2333-2338

2008

-

2

-

1

-

2

-

3

-

1

-

2

-

2

-

1

-

3

-

1

-

699215

Signorelli

Polymorphisms of steroid 5-alp ...

Homo sapiens

J. Endocrinol. Invest.

31

1092-1097

2008

-

4

-

4

-

684794

Lu

Changes in aortic endothelium ...

Rattus norvegicus

Asian J. Androl.

9

843-847

2007

-

3

-

1

-

1

-

687017

Verdi

Finasteride, a 5alpha-reductas ...

Rattus norvegicus

Horm. Behav.

51

605-610

2007

1

-

1

-

2

-

1

-

1

-

1

-

1

-

668021

Park Jun-Seon

Enzymatic hydrolysis of green ...

Homo sapiens

Biosci. Biotechnol. Biochem.

70

387-394

2006

-

1

-

2

-

1

-

668300

Skalba

Content of 5-alpha-reductase ( ...

Homo sapiens

Clin. Exp. Dermatol.

31

564-570

2006

-

1

-

1

-

1

-

1

-

1

-

668682

Kim Sung Hoo

A novel frameshift mutation in ...

Homo sapiens

Fertil. Steril.

85(750)

e9-e12

2006

-

1

-

1

-

2

-

1

-

1

-

668960

Elzanaty

Significant impact of 5alpha-r ...

Homo sapiens

Int. J. Androl.

29

414-420

2006

-

1

-

2

-

1

-

1

-

1

-

2

-

1

-

669624

Goodarzi

Variants in the 5alpha-reducta ...

Homo sapiens

J. Clin. Endocrinol. Metab.

91

4085-4091

2006

-

1

-

3

-

1

-

2

-

1

-

1

-

669811

Salem

Novel 5alpha-reductase inhibit ...

Homo sapiens, Rattus norvegicus

J. Med. Chem.

49

748-759

2006

-

20

-

4

-

2

-

3

-

20

-

2

-

3

-

670266

Robaire

Actions of 5alpha-reductase in ...

Rattus norvegicus

Mol. Cell. Endocrinol.

250

190-195

2006

-

3

-

2

-

1

-

3

-

1

-

670694

Agis-Balboa

Characterization of brain neur ...

Mus musculus

Proc. Natl. Acad. Sci. USA

103

14602-14607

2006

-

3

-

1

-

1

-

670738

Gleave

The effects of the dual 5alpha ...

Homo sapiens

Prostate

66

1674-1685

2006

-

1

-

1

-

2

-

1

-

1

-

1

-

1

-

740177

Park

Enzymatic hydrolysis of green ...

Homo sapiens

Biosci. Biotechnol. Biochem.

70

387-94

2006

-

2

-

1

-

2

-

2

-

1

-

3

-

2

-

1

-

2

-

1

-

662726

Luu-The

Quantitative appreciation of s ...

Mus musculus

J. Steroid Biochem. Mol. Biol.

93

269-276

2005

-

2

-

2

-

3

-

2

-

1

-

2

-

3

-

2

-

668281

Titus

Steroid 5alpha-reductase isozy ...

Homo sapiens

Clin. Cancer Res.

11

4365-4371

2005

-

1

-

1

-

1

-

2

-

1

-

1

-

669566

Festuccia

Effects of 5 alpha reductase i ...

Homo sapiens

J. Cancer Res. Clin. Oncol.

131

243-254

2005

-

1

-

2

-

2

-

3

-

1

-

2

-

3

-

670032

Lou

Regulation of aromatase and 5a ...

Homo sapiens

J. Steroid Biochem. Mol. Biol.

94

151-157

2005

1

-

2

-

3

-

1

-

3

-

655346

Torres

Precise quantitation of steroi ...

Rattus norvegicus

Endocr. Res.

30

149-157

2004

1

-

2

-

2

-

4

1

-

2

-

2

-

1

-

2

-

4

1

-

2

-

655739

Torres

Quantitation of mRNA levels of ...

Rattus norvegicus

Int. J. Biochem. Cell Biol.

36

78-88

2004

-

1

-

1

-

2

-

1

-

657354

Woelfling

Neighboring group participatio ...

Homo sapiens

Steroids

69

451-460

2004

-

7

-

2

-

1

-

1

-

1

-

7

-

7

-

1

-

1

-

655526

Torres

Differential regulation of ste ...

Rattus norvegicus

FASEB J.

17

1428-1433

2003

1

-

1

-

1

-

4

-

2

-

3

-

5

-

2

-

1

-

1

-

1

-

4

-

3

-

5

-

391399

Florin

Comamonas testosteroni 3-ketos ...

Comamonas testosteroni

J. Bacteriol.

178

3322-3330

1996

-

1

-

2

-

2

1

-

6

-

3

1

-

1

-

1

-

1

-

2

-

2

1

-

3

1

-

1

-

712201

Tóth

In vitro inhibition of testicu ...

Homo sapiens, Rattus norvegicus

Int. Urol. Nephrol.

28

337-348

1996

-

1

-

2

-

2

-

2

-

3

-

2

-

1

-

2

-

2

-

3

-

391397

Farkash

Biosynthesis of catalytically ...

Rattus norvegicus

Proc. Natl. Acad. Sci. USA

85

5824-5828

1988

-

1

-

1

-

1

-

4

-

2

-

2

-

1

-

1

-

1

-

2

-

2

-

391383

Levy

Bacterial oxidation of steroid ...

Comamonas testosteroni

J. Biol. Chem.

234

2014-2021

1959

-

16

-

1

-

2

-

1

-

16

-

2

-

1

-

5 alpha-reductase and aromatase inhibitory constituents from Brassica rapa L. pollen

Data extracted from this reference: