Organism | UniProt | Comment | Textmining |
---|---|---|---|
Kitasatospora aureofaciens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
7-chloro-5a,11a-dehydrotetracycline + reduced cosynthetic factor-1 | - |
Kitasatospora aureofaciens | 7-chlorotetracycline + oxidized cosynthetic factor-1 | - |
? | |
tetracycline + oxidized coenzyme F420 | - |
Kitasatospora aureofaciens | 5a,11a-dehydrotetracycline + reduced coenzyme F420 | - |
? |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
additional information | cosynthetic factor-1 enables Streptomyces aureofaciens to produce tetracycline instead of their 5a,11a-dehydro analogues | Kitasatospora aureofaciens | |
additional information | isolation of Cosynthetic Factor I, required for catayltic activity. The factor is dialysable and stable to autoclaving over the pH range of 1 to 10 | Kitasatospora aureofaciens |