BRENDA - Enzyme Database
show all sequences of 1.3.8.8

Purification and properties of acyl coenzyme A dehydrogenases from bovine liver. Formation of 2-trans,4-cis-decadienoyl coenzyme A

Dommes, V.; Kunau, W.H.; J. Biol. Chem. 259, 1789-1797 (1984)

Data extracted from this reference:

KM Value [mM]
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
0.13
-
decanoyl-CoA
-
Bos taurus
0.2
-
dodecanoyl-CoA
-
Bos taurus
0.2
-
5-cis-decenoyl-CoA
-
Bos taurus
0.23
-
octanoyl-CoA
-
Bos taurus
0.24
-
cis,cis,cis,cis-4,7,10,13-hexadecatetraenoyl-CoA
-
Bos taurus
0.25
-
4-cis-decenoyl-CoA
-
Bos taurus
0.29
-
stearoyl-CoA
-
Bos taurus
0.32
-
4-cis,7-cis-decadienoyl-CoA
-
Bos taurus
0.32
-
6-cis-decenoyl-CoA
-
Bos taurus
0.38
-
tetradecanoyl-CoA
-
Bos taurus
0.55
-
hexanoyl-CoA
-
Bos taurus
0.78
-
palmitoyl-CoA
-
Bos taurus
Localization
Localization
Commentary
Organism
GeneOntology No.
Textmining
mitochondrion
-
Bos taurus
5739
-
Molecular Weight [Da]
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
172000
-
gel electrophoresis
Bos taurus
Organism
Organism
UniProt
Commentary
Textmining
Bos taurus
-
-
-
Purification (Commentary)
Purification (Commentary)
Organism
40-70% ammonium sulfate precipitation, Sephadex G-150, DEAE-cellulose, preparative electrophoresis
Bos taurus
Source Tissue
Source Tissue
Commentary
Organism
Textmining
liver
-
Bos taurus
-
Specific Activity [micromol/min/mg]
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
32.5
-
purified enzyme, decanoyl-CoA
Bos taurus
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
Substrate Product ID
4-cis-7-cis-decadienoyl-CoA + Meldola's Blue
-
391275
Bos taurus
2-trans-4,7-cis,cis-decatrienoyl-CoA + reduced meldola blue
-
391275
Bos taurus
?
4-cis-decenoyl-CoA + Meldola's Blue
-
391275
Bos taurus
2-trans-4-cis-decadienoyl-CoA + reduced meldola blue
-
391275
Bos taurus
?
5-cis-decenoyl-CoA + Meldola's Blue
-
391275
Bos taurus
2-trans-5-cis-decadienoyl-CoA + reduced meldola blue
-
391275
Bos taurus
?
6-cis-decenoyl-CoA + Meldola's Blue
-
391275
Bos taurus
2-trans-6-cis-decadienoyl-CoA + reduced meldola blue
-
391275
Bos taurus
?
cis,cis,cis,cis-4,7,10,13-hexadecatetraenoyl-CoA + Meldola's Blue
-
391275
Bos taurus
2-trans-4,7,10,13-cis,cis,cis,cis-hexadecapentaenoyl-CoA + reduced meldola blue
-
391275
Bos taurus
?
decanoyl-CoA + Meldola's Blue
-
391275
Bos taurus
2-decenoyl-CoA + reduced meldola blue
trans-isomer
391275
Bos taurus
?
dodecanoyl-CoA + Meldola's Blue
-
391275
Bos taurus
2-dodecenoyl-CoA + reduced meldola blue
trans-isomer
391275
Bos taurus
?
hexanoyl-CoA + Meldola's Blue
-
391275
Bos taurus
(2E)-2-hexenoyl-CoA + reduced meldola blue
trans-isomer
391275
Bos taurus
?
octanoyl-CoA + Meldola's Blue
-
391275
Bos taurus
(2E)-2-octenoyl-CoA + reduced meldola blue
trans-isomer
391275
Bos taurus
?
palmitoyl-CoA + Meldola's Blue
-
391275
Bos taurus
2-hexadecenoyl-CoA + reduced meldola blue
trans-isomer
391275
Bos taurus
?
stearoyl-CoA + Meldola's Blue
-
391275
Bos taurus
2-octadecenoyl-CoA + reduced meldola blue
trans-isomer
391275
Bos taurus
?
tetradecanoyl-CoA + Meldola's Blue
-
391275
Bos taurus
2-tetradecenoyl-CoA + reduced meldola blue
trans-isomer
391275
Bos taurus
?
Subunits
Subunits
Commentary
Organism
tetramer
4 * 38000-45200, SDS-PAGE
Bos taurus
KM Value [mM] (protein specific)
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
0.13
-
decanoyl-CoA
-
Bos taurus
0.2
-
dodecanoyl-CoA
-
Bos taurus
0.2
-
5-cis-decenoyl-CoA
-
Bos taurus
0.23
-
octanoyl-CoA
-
Bos taurus
0.24
-
cis,cis,cis,cis-4,7,10,13-hexadecatetraenoyl-CoA
-
Bos taurus
0.25
-
4-cis-decenoyl-CoA
-
Bos taurus
0.29
-
stearoyl-CoA
-
Bos taurus
0.32
-
4-cis,7-cis-decadienoyl-CoA
-
Bos taurus
0.32
-
6-cis-decenoyl-CoA
-
Bos taurus
0.38
-
tetradecanoyl-CoA
-
Bos taurus
0.55
-
hexanoyl-CoA
-
Bos taurus
0.78
-
palmitoyl-CoA
-
Bos taurus
Localization (protein specific)
Localization
Commentary
Organism
GeneOntology No.
Textmining
mitochondrion
-
Bos taurus
5739
-
Molecular Weight [Da] (protein specific)
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
172000
-
gel electrophoresis
Bos taurus
Purification (Commentary) (protein specific)
Commentary
Organism
40-70% ammonium sulfate precipitation, Sephadex G-150, DEAE-cellulose, preparative electrophoresis
Bos taurus
Source Tissue (protein specific)
Source Tissue
Commentary
Organism
Textmining
liver
-
Bos taurus
-
Specific Activity [micromol/min/mg] (protein specific)
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
32.5
-
purified enzyme, decanoyl-CoA
Bos taurus
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
ID
4-cis-7-cis-decadienoyl-CoA + Meldola's Blue
-
391275
Bos taurus
2-trans-4,7-cis,cis-decatrienoyl-CoA + reduced meldola blue
-
391275
Bos taurus
?
4-cis-decenoyl-CoA + Meldola's Blue
-
391275
Bos taurus
2-trans-4-cis-decadienoyl-CoA + reduced meldola blue
-
391275
Bos taurus
?
5-cis-decenoyl-CoA + Meldola's Blue
-
391275
Bos taurus
2-trans-5-cis-decadienoyl-CoA + reduced meldola blue
-
391275
Bos taurus
?
6-cis-decenoyl-CoA + Meldola's Blue
-
391275
Bos taurus
2-trans-6-cis-decadienoyl-CoA + reduced meldola blue
-
391275
Bos taurus
?
cis,cis,cis,cis-4,7,10,13-hexadecatetraenoyl-CoA + Meldola's Blue
-
391275
Bos taurus
2-trans-4,7,10,13-cis,cis,cis,cis-hexadecapentaenoyl-CoA + reduced meldola blue
-
391275
Bos taurus
?
decanoyl-CoA + Meldola's Blue
-
391275
Bos taurus
2-decenoyl-CoA + reduced meldola blue
trans-isomer
391275
Bos taurus
?
dodecanoyl-CoA + Meldola's Blue
-
391275
Bos taurus
2-dodecenoyl-CoA + reduced meldola blue
trans-isomer
391275
Bos taurus
?
hexanoyl-CoA + Meldola's Blue
-
391275
Bos taurus
(2E)-2-hexenoyl-CoA + reduced meldola blue
trans-isomer
391275
Bos taurus
?
octanoyl-CoA + Meldola's Blue
-
391275
Bos taurus
(2E)-2-octenoyl-CoA + reduced meldola blue
trans-isomer
391275
Bos taurus
?
palmitoyl-CoA + Meldola's Blue
-
391275
Bos taurus
2-hexadecenoyl-CoA + reduced meldola blue
trans-isomer
391275
Bos taurus
?
stearoyl-CoA + Meldola's Blue
-
391275
Bos taurus
2-octadecenoyl-CoA + reduced meldola blue
trans-isomer
391275
Bos taurus
?
tetradecanoyl-CoA + Meldola's Blue
-
391275
Bos taurus
2-tetradecenoyl-CoA + reduced meldola blue
trans-isomer
391275
Bos taurus
?
Subunits (protein specific)
Subunits
Commentary
Organism
tetramer
4 * 38000-45200, SDS-PAGE
Bos taurus
Other publictions for EC 1.3.8.8
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Synonyms
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
740984
Rudolf
A genetically amenable platens ...
Streptomyces platensis, Streptomyces platensis SB12029
Mol. Biosyst.
11
2717-2726
2015
-
-
-
-
-
-
-
-
-
-
-
-
-
4
-
-
-
-
-
-
-
-
2
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
1
1
-
-
-
710755
Li
Purification, crystallization ...
Caenorhabditis elegans
Acta Crystallogr. Sect. F
66
426-430
2010
-
-
1
1
-
-
-
-
1
-
-
-
-
1
-
-
1
-
-
-
-
-
-
1
1
-
-
-
-
-
-
-
1
-
-
-
-
-
1
1
1
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
2
2
-
-
-
713044
Maher
Low expression of long-chain a ...
Homo sapiens
Mol. Genet. Metab.
100
163-167
2010
-
-
1
-
-
-
-
-
1
-
-
1
-
8
-
-
-
-
-
6
-
-
1
-
2
-
-
-
-
-
-
-
1
-
-
-
-
-
1
1
-
-
-
-
-
-
-
1
-
-
1
-
-
-
-
-
6
-
-
1
-
-
-
-
-
-
-
-
-
-
1
1
-
-
-
700233
Arnold
A Delphi clinical practice pro ...
Homo sapiens
Mol. Genet. Metab.
96
85-90
2009
-
1
-
-
-
-
-
-
1
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
700578
Korematsu
Novel mutation of early, perin ...
Homo sapiens
Pediatr. Neurol.
41
151-153
2009
-
-
-
-
2
-
-
2
1
-
-
-
-
1
-
-
-
-
-
1
-
-
2
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
2
1
-
-
-
-
-
-
-
-
1
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
700905
ter Veld
A novel tandem mass spectromet ...
Homo sapiens
PLoS ONE
4
e6449
2009
-
1
-
-
2
-
-
-
-
-
-
-
-
4
-
-
-
-
-
1
4
-
3
-
6
1
-
-
-
1
-
-
-
-
-
-
-
1
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
4
-
3
-
1
-
-
-
1
-
-
-
-
-
-
-
-
-
687810
McAndrew
Structural basis for substrate ...
Homo sapiens
J. Biol. Chem.
283
9435-9443
2008
-
-
1
2
-
-
-
-
1
-
-
-
-
3
-
-
2
-
-
-
-
-
2
1
4
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
2
-
-
-
-
-
-
1
-
-
-
-
-
-
2
-
-
-
-
2
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
689339
Primassin
Carnitine supplementation indu ...
Mus musculus
Pediatr. Res.
63
632-637
2008
-
1
-
-
-
-
-
-
-
-
-
-
-
5
-
-
-
-
-
-
-
-
2
-
2
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
689340
Tajima
Development of a new enzymatic ...
Homo sapiens
Pediatr. Res.
64
667-672
2008
-
-
-
-
-
-
-
-
-
-
-
-
-
5
-
-
-
-
-
1
-
-
1
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
699301
Beattie
Recombinant adeno-associated v ...
Mus musculus
J. Gene Med.
10
1113-1123
2008
-
1
1
-
-
-
-
-
1
-
1
-
-
12
-
-
-
-
-
2
2
-
2
-
2
1
-
-
-
1
-
-
-
-
-
-
-
1
1
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
-
2
2
-
2
-
1
-
-
-
1
-
-
-
-
-
-
-
-
-
684281
Gobin-Limballe
Genetic basis for correction o ...
Homo sapiens
Am. J. Hum. Genet.
81
1133-1143
2007
1
-
-
-
-
-
-
-
1
-
-
-
-
2
-
-
-
-
-
1
-
-
2
-
2
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
684346
Werdich
Polymorphic ventricular tachyc ...
Mus musculus
Am. J. Physiol. Heart Circ. Physiol.
292
H2202-H2211
2007
-
-
-
-
1
-
-
-
1
-
-
-
-
4
-
-
-
-
-
3
-
-
1
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
-
-
-
-
-
-
3
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
686160
Law
Novel missense mutations in th ...
Homo sapiens
Clin. Chim. Acta
375
173-174
2007
-
-
-
-
2
-
-
-
-
-
-
-
-
1
-
-
-
-
-
2
-
-
1
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
688181
Zia
Very long chain acyl-CoA dehyd ...
Homo sapiens
J. Inherit. Metab. Dis.
30
817-817
2007
-
-
-
-
-
-
-
-
1
-
-
1
-
2
-
-
-
-
-
-
-
-
1
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
689007
Goetzman
Expression and characterizatio ...
Homo sapiens
Mol. Genet. Metab.
91
138-147
2007
-
-
2
-
12
-
-
-
2
-
1
-
-
3
-
-
1
-
-
-
-
-
14
1
4
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
12
-
-
-
-
-
2
-
1
-
-
-
-
1
-
-
-
-
14
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
689761
Zhang
Mitochondrial dysfunction due ...
Mus musculus
Proc. Natl. Acad. Sci. USA
104
17075-17080
2007
-
-
-
-
-
-
-
-
1
-
-
-
-
4
-
-
-
-
-
2
-
-
2
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
2
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
663777
Takagi
Localization of a long-chain a ...
Mus musculus
Arch. Biochem. Biophys.
446
161-166
2006
-
1
-
-
-
-
-
-
-
-
-
-
-
4
-
-
-
-
-
3
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
671771
Oey
Acyl-CoA dehydrogenase 9 (ACAD ...
Homo sapiens
Biochem. Biophys. Res. Commun.
346
33-37
2006
-
1
-
-
-
-
-
-
-
-
-
-
-
4
-
-
-
-
-
8
-
-
2
-
2
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
8
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
676027
Merritt II
In vitro characterization and ...
Homo sapiens
Mol. Genet. Metab.
88
351-358
2006
-
1
1
-
1
-
-
-
-
-
1
-
-
9
-
-
1
-
-
3
-
1
1
-
1
-
-
-
-
-
-
-
-
-
-
-
-
1
1
-
-
1
-
-
-
-
-
-
-
1
-
-
-
-
1
-
3
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
671275
Yamada
Long-chain acyl-CoA hydrolase ...
Homo sapiens, Mus musculus, Rattus norvegicus
Amino Acids
28
273-278
2005
1
1
3
-
-
-
-
-
7
-
3
-
-
3
-
-
3
-
-
12
-
-
8
2
18
-
-
-
-
-
-
-
-
-
-
-
1
1
3
-
-
-
-
-
-
-
-
7
-
3
-
-
-
-
3
-
12
-
-
8
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
671584
Mason
Inhibition of very long chain ...
Rattus norvegicus
Arch. Biochem. Biophys.
437
138-143
2005
1
1
-
-
-
-
-
-
1
-
-
-
-
2
-
-
-
-
-
2
-
-
2
-
1
-
-
-
-
-
-
-
-
-
-
-
1
1
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
2
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
673935
Djouadi
Bezafibrate increases very-lon ...
Homo sapiens
Hum. Mol. Genet.
14
2695-2703
2005
1
-
-
-
3
-
-
-
-
-
-
-
-
3
-
-
-
-
-
2
-
-
1
-
1
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
656692
Clark-Taylor
Is autism a disorder of fatty ...
Homo sapiens
Med. Hypotheses
62
970-975
2004
-
-
-
-
-
-
-
-
1
-
-
1
-
3
-
-
-
-
-
-
-
-
4
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
656816
Berger
Disrupted blastocoele formatio ...
Mus musculus
Mol. Genet. Metab.
82
266-272
2004
-
-
-
-
1
-
-
-
-
-
-
-
-
4
-
-
-
-
-
1
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
653212
Takagi
Inducible expression of long-c ...
Mus musculus
Mol. Cell. Biochem.
252
379-385
2003
-
-
1
-
-
-
-
-
-
-
-
1
-
3
-
-
-
-
-
2
-
-
2
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
2
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
656313
Tani
Two acyl-CoA dehydrogenases of ...
Acinetobacter sp., Acinetobacter sp. M-1
J. Biosci. Bioeng.
94
326-329
2002
-
-
1
-
-
-
6
1
-
-
3
2
-
6
-
-
1
-
-
-
-
-
2
1
1
-
-
1
-
1
-
1
1
-
-
-
-
-
1
1
-
-
-
-
6
-
1
-
-
3
2
-
-
-
1
-
-
-
-
2
1
-
-
1
-
1
-
1
-
-
-
-
-
-
-
394667
Bode
Identification, separation, an ...
Helianthus annuus
Plant Physiol.
119
1305-1314
1999
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
1
-
-
1
-
-
7
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
1
-
-
7
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
394665
Battaile
Human long chain, very long ch ...
Homo sapiens
Biochim. Biophys. Acta
1390
333-338
1998
-
-
-
-
-
-
-
-
1
-
-
-
-
2
-
-
-
-
-
2
3
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
2
3
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
394666
Kurtz
Structural characterization of ...
Mus musculus
Mamm. Genome
9
361-365
1998
-
-
1
-
-
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
391371
Eder
Characterization of human and ...
Homo sapiens, Sus scrofa
Eur. J. Biochem.
245
600-607
1997
-
-
1
-
-
-
2
16
-
-
3
-
-
7
-
-
2
-
-
1
1
-
14
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
2
-
16
-
-
3
-
-
-
-
2
-
1
1
-
14
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
391369
Nandy
Medium-long-chain chimeric hum ...
Homo sapiens
Biochemistry
35
12402-12411
1996
-
-
1
-
-
-
1
-
-
-
-
-
-
3
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
394662
Aoyama
Purification of human very-lon ...
Homo sapiens, Rattus norvegicus
J. Clin. Invest.
95
2465-2473
1995
-
-
-
-
-
-
-
-
1
-
-
-
-
5
-
-
-
-
-
3
-
-
6
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
3
-
-
6
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
394661
Djordjevic
Identification of the catalyti ...
Homo sapiens
Biochemistry
33
4258-4264
1994
-
-
1
-
1
-
-
-
-
-
-
-
-
5
-
-
-
-
-
-
-
-
3
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
3
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
394660
Ijlst
-
A simple spectrophotometric as ...
Homo sapiens
Ann. Clin. Biochem.
30
293-297
1993
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
391047
Suzuki
Compartmentation of dicarboxyl ...
Rattus norvegicus
Biochim. Biophys. Acta
990
25-30
1989
-
-
-
-
-
-
-
5
1
-
-
-
-
1
-
-
1
-
-
1
-
-
5
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
5
1
-
-
-
-
-
-
1
-
1
-
-
5
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
391199
Matsubara
Molecular cloning and nucleoti ...
Rattus norvegicus
J. Biol. Chem.
264
16321-16331
1989
-
-
1
-
-
-
-
-
1
-
1
-
-
1
-
-
-
-
-
1
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
-
1
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
394659
Veitch
Altered acyl-CoA metabolism in ...
Rattus norvegicus
Biochim. Biophys. Acta
1006
335-343
1989
-
-
-
-
-
-
-
-
1
-
-
-
-
1
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
391298
Veitch
Effects of riboflavin deficien ...
Rattus norvegicus
Biochem. J.
254
477-481
1988
1
-
-
-
-
-
-
-
1
-
-
-
-
1
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
1
-
-
1
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
394658
Hughes
Regulation of fatty acid degra ...
Escherichia coli
J. Bacteriol.
170
1666-1671
1988
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
8
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
8
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
391265
Ikeda
Biosynthesis of four rat liver ...
Rattus norvegicus
Arch. Biochem. Biophys.
252
662-674
1987
-
-
-
-
-
-
-
-
1
-
-
-
-
4
-
-
1
-
-
1
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
1
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
391325
Chalmers
-
Fatty acid oxidation in cultur ...
Homo sapiens
Biochem. Soc. Trans.
15
489-491
1987
-
-
-
-
-
-
-
-
1
-
-
-
-
1
-
-
-
-
-
2
-
-
5
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
2
-
-
5
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
394642
Yamada
Participation of peroxisomes i ...
Rattus norvegicus
Biochim. Biophys. Acta
921
292-301
1987
-
-
-
-
-
-
-
3
1
-
-
-
-
1
-
-
-
-
-
1
-
-
5
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
3
1
-
-
-
-
-
-
-
-
1
-
-
5
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
391268
Ikeda
Spectroscopic analysis of the ...
Rattus norvegicus
Biochemistry
24
7192-7199
1985
-
-
-
-
-
-
-
-
1
-
-
-
-
1
-
-
1
-
-
1
-
-
8
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
1
-
-
8
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
391270
Okamura-Ikeda
An essential cysteine residue ...
Rattus norvegicus
J. Biol. Chem.
260
1338-1345
1985
-
-
-
-
-
-
8
-
1
-
-
-
-
1
-
-
1
-
-
1
2
-
1
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
8
-
-
1
-
-
-
-
-
-
1
-
1
2
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
391271
Ikeda
Mechanism of action of short-c ...
Rattus norvegicus
J. Biol. Chem.
260
1326-1337
1985
-
-
-
-
-
-
3
-
1
-
-
-
-
1
-
-
1
-
-
1
-
-
2
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
3
-
-
1
-
-
-
-
-
-
1
-
1
-
-
2
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
391272
Ikeda
Purification and characterizat ...
Rattus norvegicus
J. Biol. Chem.
260
1311-1325
1985
-
-
-
-
-
-
1
10
1
-
1
-
-
2
-
-
1
-
-
1
15
-
22
1
-
-
-
-
-
-
-
1
1
-
-
-
-
-
-
1
-
-
-
-
1
-
10
1
-
1
-
-
-
-
1
-
1
15
-
22
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
391275
Dommes
Purification and properties of ...
Bos taurus
J. Biol. Chem.
259
1789-1797
1984
-
-
-
-
-
-
-
12
1
-
1
-
-
2
-
-
1
-
-
1
1
-
12
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
12
1
-
1
-
-
-
-
1
-
1
1
-
12
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
391203
Ikeda
Separation and properties of f ...
Rattus norvegicus
J. Biol. Chem.
258
1066-1076
1983
-
-
-
-
-
-
-
2
1
-
-
-
-
1
-
-
1
-
-
1
-
-
7
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
2
1
-
-
-
-
-
-
1
-
1
-
-
7
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
394652
Gohil
-
Fatty acid oxidation in human ...
Homo sapiens
Biochem. Soc. Trans.
11
728-729
1983
-
-
-
-
-
-
-
-
1
-
-
-
-
1
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
391282
Furuta
Purification and properties of ...
Rattus norvegicus
J. Biochem.
90
1739-1750
1981
-
-
-
-
-
-
-
1
1
-
1
-
-
5
-
-
1
-
-
1
3
1
20
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
1
-
1
-
-
-
-
1
-
1
3
1
20
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
394651
Bauche
2-Mercaptoacetate administrati ...
Rattus norvegicus
Biochem. J.
196
803-809
1981
-
-
-
-
-
-
1
-
1
-
-
-
-
2
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
394653
Furuta
Induction of acyl-CoA dehydrog ...
Rattus norvegicus
J. Biochem.
90
1751-1756
1981
-
-
-
-
-
-
-
-
1
-
-
-
-
1
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
391361
Hall
Acyl coenzyme A dehydrogenases ...
Bos taurus
Arch. Biochem. Biophys.
177
402-414
1976
-
-
-
-
-
-
1
2
1
-
-
-
-
1
-
-
1
-
-
2
4
-
3
1
-
-
-
-
1
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
1
-
2
1
-
-
-
-
-
-
1
-
2
4
-
3
1
-
-
-
1
-
-
-
-
-
-
-
-
-
-
394650
Hauge
On the mechanism of dehydrogen ...
Sus scrofa
J. Biol. Chem.
219
727-733
1956
-
-
-
-
-
-
-
-
1
-
1
-
-
1
-
-
1
-
-
1
-
-
8
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
1
-
1
-
-
-
-
1
-
1
-
-
8
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-