Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.3.8.7 extracted from

  • Ikeda, Y.; Hine, D.G.; Okamura-Ikeda, K.; Tanaka, K.
    Mechanism of action of short-chain, medium-chain, and long-chain acyl-CoA dehydrogenases. Direct evidence for carbanion formation as an intermediate step using enzyme-catalyzed C-2 proton/deuteron exchange in the absence of C-3 exchange (1985), J. Biol. Chem., 260, 1326-1337.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
HgCl2
-
Rattus norvegicus
Methylmercury iodide
-
Rattus norvegicus
p-chloromercuribenzoate
-
Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Rattus norvegicus

Reaction

Reaction Comment Organism Reaction ID
a medium-chain acyl-CoA + electron-transfer flavoprotein = a medium-chain trans-2,3-dehydroacyl-CoA + reduced electron-transfer flavoprotein mechanism, proton abstraction from C-2 of the substrate and hydride transfer from C-3 to the N-5 position of the flavin Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
Rattus norvegicus
-

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
3.3
-
octanoyl-CoA C-2 proton/deuteron exchange Rattus norvegicus
27.2
-
octanoyl-CoA
-
Rattus norvegicus