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Literature summary for 1.3.8.7 extracted from

  • Ikeda, Y.; Dabrowski, C.; Tanaka, K.
    Separation and properties of five distinct acyl-CoA dehydrogenases from rat liver mitochondria. Identification of a new 2-methyl branched chain acyl-CoA dehydrogenase (1983), J. Biol. Chem., 258, 1066-1076.
    View publication on PubMed

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0024
-
FAD
-
Rattus norvegicus
1.47
-
octanoyl-CoA with phenazine methosulfate Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acyl-CoA + acceptor electron acceptor: phenazine methosulfate Rattus norvegicus 2,3-dehydroacyl-CoA + reduced acceptor
-
?
acyl-CoA + acceptor specific for chain lengths C6-C12 Rattus norvegicus 2,3-dehydroacyl-CoA + reduced acceptor
-
?
acyl-CoA + acceptor intermediary electron acceptor: 2,6-dichloroindophenol Rattus norvegicus 2,3-dehydroacyl-CoA + reduced acceptor
-
?
acyl-CoA + acceptor final electron acceptor: 8-dimethylamino-2,3-benzophenoxazinium chloride, trivial name meldola's blue Rattus norvegicus 2,3-dehydroacyl-CoA + reduced acceptor
-
?
decanoyl-CoA + acceptor 72% of activity with hexanoyl-CoA Rattus norvegicus 2-decenoyl-CoA + reduced acceptor
-
?
decanoyl-CoA + phenazine methosulfate + 2,6-dichloroindophenol
-
Rattus norvegicus 2-trans-decenoyl-CoA + reduced acceptor
-
?
heptadecan-2-onyl-dethio-CoA + phenazine methosulfate + 2,6-dichloroindophenol
-
Rattus norvegicus ?
-
?
hexadecanoyl-CoA + acceptor 55% of activity with hexanoyl-CoA Rattus norvegicus 2-hexadecenoyl-CoA + reduced acceptor
-
?
hexanoyl-CoA + acceptor best substrate Rattus norvegicus 2-hexenoyl-CoA + reduced acceptor
-
?
hexanoyl-CoA + phenazine methosulfate + 2,6-dichloroindophenol
-
Rattus norvegicus 2-trans-hexenoyl-CoA + reduced acceptor
-
?
lauroyl-CoA + phenazine methosulfate + 2,6-dichloroindophenol
-
Rattus norvegicus 2-trans-dodecenoyl-CoA + reduced acceptor
-
?
n-octanoyl-CoA + phenazine methosulfate + 2,6-dichloroindophenol 82% of activity with hexanoyl-CoA Rattus norvegicus 2-octenoyl-CoA + reduced acceptor
-
?
n-tetradecanoyl-CoA + phenazine methosulfate + 2,6-dichloroindophenol best substrate for long-chain acyl-CoA dehydrogenase Rattus norvegicus 2-tetradecenoyl-CoA + reduced acceptor
-
?
pentanoyl-CoA + acceptor 68% of activity with hexanoyl-CoA Rattus norvegicus 2-pentenoyl-CoA + reduced acceptor
-
?

Cofactor

Cofactor Comment Organism Structure
FAD FAD is readily lost upon purification Rattus norvegicus