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Literature summary for 1.3.8.14 extracted from

  • Thomas, M.; Burkart, M.; Walsh, C.
    Conversion of L-proline to pyrrolyl-2-carboxyl-S-PCP during undecylprodigiosin and pyoluteorin biosynthesis (2002), Chem. Biol., 9, 171-184 .
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli BL21(DE3) cells Streptomyces coelicolor

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
S-(L-prolyl)-[peptidyl-carrier protein] + electron-transfer flavoprotein Streptomyces coelicolor
-
S-(1H-pyrrole-2-carbonyl)-[peptidyl-carrier protein] + reduced electron-transfer flavoprotein
-
?
S-(L-prolyl)-[peptidyl-carrier protein] + electron-transfer flavoprotein Streptomyces coelicolor A(3)2
-
S-(1H-pyrrole-2-carbonyl)-[peptidyl-carrier protein] + reduced electron-transfer flavoprotein
-
?

Organism

Organism UniProt Comment Textmining
Streptomyces coelicolor
-
-
-
Streptomyces coelicolor A(3)2
-
-
-

Purification (Commentary)

Purification (Comment) Organism
Q sepharose column chromatography Streptomyces coelicolor

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information no activity with L-prolyl-S-CoA Streptomyces coelicolor ?
-
?
additional information no activity with L-prolyl-S-CoA Streptomyces coelicolor A(3)2 ?
-
?
S-(L-prolyl)-[peptidyl-carrier protein] + electron-transfer flavoprotein
-
Streptomyces coelicolor S-(1H-pyrrole-2-carbonyl)-[peptidyl-carrier protein] + reduced electron-transfer flavoprotein
-
?
S-(L-prolyl)-[peptidyl-carrier protein] + electron-transfer flavoprotein
-
Streptomyces coelicolor A(3)2 S-(1H-pyrrole-2-carbonyl)-[peptidyl-carrier protein] + reduced electron-transfer flavoprotein
-
?

Subunits

Subunits Comment Organism
? x * 40000, SDS-PAGE Streptomyces coelicolor

Synonyms

Synonyms Comment Organism
L-prolyl-S-PCP dehydrogenase
-
Streptomyces coelicolor
pltE
-
Streptomyces coelicolor
redW
-
Streptomyces coelicolor
SC2E9.20
-
Streptomyces coelicolor

Cofactor

Cofactor Comment Organism Structure
FAD
-
Streptomyces coelicolor