Inhibitors | Comment | Organism | Structure |
---|---|---|---|
3-nitropropanoate | treatment with 3-nitroproprionate dissipates the membrane potential of wild-type or Sdh1 mutant cells under hypoxia but not that of cells grown aerobically | Mycolicibacterium smegmatis |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | - |
Mycolicibacterium smegmatis | 16020 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mycolicibacterium smegmatis | A0QPJ1 and A0QPJ2 and A0QPJ3 and A0QPJ4 and A0QPJ5 | isoform Sdh1 is encoded by a five-gene operon. A0QPJ1 i.e. gene MSMEG_0416, A0QPJ2 i.e. gene MSMEG_0417, A0QPJ3 i.e. gene MSMEG_0418, A0QPJ4 i.e. gene MSMEG_0419, A0QPJ5 i.e. gene MSMEG_0420 | - |
Mycolicibacterium smegmatis | A0QT07 and A0QT08 and A0QT09 and A0QT10 | isoform Sdh2 is encoded by a five-gene operon. A0QT07 i.e. gene MSMEG_1669, A0QT08 i.e. gene MSMEG_1670, A0QT09 i.e. gene MSMEG_1671, A0QT10 i.e. gene MSMEG_1672 | - |
Mycolicibacterium smegmatis ATCC 700084 | A0QPJ1 and A0QPJ2 and A0QPJ3 and A0QPJ4 and A0QPJ5 | isoform Sdh1 is encoded by a five-gene operon. A0QPJ1 i.e. gene MSMEG_0416, A0QPJ2 i.e. gene MSMEG_0417, A0QPJ3 i.e. gene MSMEG_0418, A0QPJ4 i.e. gene MSMEG_0419, A0QPJ5 i.e. gene MSMEG_0420 | - |
Mycolicibacterium smegmatis ATCC 700084 | A0QT07 and A0QT08 and A0QT09 and A0QT10 | isoform Sdh2 is encoded by a five-gene operon. A0QT07 i.e. gene MSMEG_1669, A0QT08 i.e. gene MSMEG_1670, A0QT09 i.e. gene MSMEG_1671, A0QT10 i.e. gene MSMEG_1672 | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
succinate + 2,6-dichlorophenolindophenol | - |
Mycolicibacterium smegmatis | fumarate + reduced 2,6-dichlorophenolindophenol | - |
ir | |
succinate + 2,6-dichlorophenolindophenol | - |
Mycolicibacterium smegmatis ATCC 700084 | fumarate + reduced 2,6-dichlorophenolindophenol | - |
ir |
Synonyms | Comment | Organism |
---|---|---|
MSMEG_0416 | - |
Mycolicibacterium smegmatis |
MSMEG_0417 | - |
Mycolicibacterium smegmatis |
MSMEG_0418 | - |
Mycolicibacterium smegmatis |
MSMEG_0419 | - |
Mycolicibacterium smegmatis |
MSMEG_0420 | - |
Mycolicibacterium smegmatis |
MSMEG_1669 | - |
Mycolicibacterium smegmatis |
MSMEG_1670 | - |
Mycolicibacterium smegmatis |
MSMEG_1671 | - |
Mycolicibacterium smegmatis |
MSMEG_1672 | - |
Mycolicibacterium smegmatis |
SDH1 | - |
Mycolicibacterium smegmatis |
SDH2 | - |
Mycolicibacterium smegmatis |
General Information | Comment | Organism |
---|---|---|
physiological function | deletion of the sdh1 operon does not yield any growth phenotypes on succinate or other nonfermentable carbon sources | Mycolicibacterium smegmatis |
physiological function | presence of the Sdh2 operon is essential for growth. Isoform Sdh2 is the generator of the membrane potential under hypoxia | Mycolicibacterium smegmatis |