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Literature summary for 1.3.5.1 extracted from

  • Xiong, L.; Zhu, X.L.; Gao, H.W.; Fu, Y.; Hu, S.Q.; Jiang, L.N.; Yang, W.C.; Yang, G.F.
    Discovery of potent succinate-ubiquinone oxidoreductase inhibitors via pharmacophore-linked fragment virtual screening approach (2016), J. Agric. Food Chem., 64, 4830-4837 .
    View publication on PubMed
Search for more literature for 1.3.5.1

Inhibitors

Inhibitors Comment Organism Structure
3-(difluoromethyl)-1-methyl-N-(1-[(2-bromophenyl)methyl]indol-7-yl)-1H-pyrazole-4-carboxamide compound exhibits good preventive effects against Rhizoctonia solani Rhizoctonia solani
3-(difluoromethyl)-1-methyl-N-(1-[(3,5-dimethylphenyl)methyl]indol-7-yl)-1H-pyrazole-4-carboxamide noncompetitive inhibition with respect to cytochrome c and 2,6-dichlorophenol indophenol Sus scrofa
3-(difluoromethyl)-1-methyl-N-(1-[(3-methylphenyl)methyl]indol-7-yl)-1H-pyrazole-4-carboxamide compound exhibits good preventive effects against Rhizoctonia solani Rhizoctonia solani
penthiopyrad noncompetitie Sus scrofa

Organism

Organism UniProt Comment Textmining
Rhizoctonia solani
-
-
-
Sus scrofa
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
succinate + 2,6-dichlorophenol indophenol
-
 Sus scrofa fumarate + reduced 2,6-dichlorophenol indophenol
-
 ?
succinate + 2,6-dichlorophenol indophenol
-
 Rhizoctonia solani fumarate + reduced 2,6-dichlorophenol indophenol
-
 ?

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.000034
-
 3-(difluoromethyl)-1-methyl-N-(1-[(3,5-dimethylphenyl)methyl]indol-7-yl)-1H-pyrazole-4-carboxamide pH not specified in the publication, temperature not specified in the publication Sus scrofa
0.00033
-
 penthiopyrad pH not specified in the publication, temperature not specified in the publication Sus scrofa

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.00004
-
 pH not specified in the publication, temperature not specified in the publication Sus scrofa 3-(difluoromethyl)-1-methyl-N-(1-[(3,5-dimethylphenyl)methyl]indol-7-yl)-1H-pyrazole-4-carboxamide
0.00053
-
 pH not specified in the publication, temperature not specified in the publication Sus scrofa penthiopyrad