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Literature summary for 1.3.5.1 extracted from
- Acidianus ambivalens complex II typifies a novel family of succinate dehydrogenases (2001), Biochem. Biophys. Res. Commun., 281, 141-150.
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| membrane | membrane anchoring based on the amphipathic nature of the putative helices found in subunit SdhC, is suggested | Acidianus ambivalens | 16020 | - |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Iron | the enzyme complex contains 10 Fe atoms. It contains the canonical centres S1 ([2Fe-2S]+2/+1) and S2 ([4Fe-4S]+2/+1) but lacks centre S3 ([3Fe-4S]+1/0). The iron-sulfur subunit contains an extra cysteine that may allow the binding of a new centre, most probably a tetranuclear one | Acidianus ambivalens |  |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 14000 | - |
x * 67000 + x * 33000 + x * 28000 + x * 14000, SDS-PAGE | Acidianus ambivalens |
| 28000 | - |
x * 67000 + x * 33000 + x * 28000 + x * 14000, SDS-PAGE | Acidianus ambivalens |
| 33000 | - |
x * 67000 + x * 33000 + x * 28000 + x * 14000, SDS-PAGE | Acidianus ambivalens |
| 67000 | - |
x * 67000 + x * 33000 + x * 28000 + x * 14000, SDS-PAGE | Acidianus ambivalens |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| succinate + caldariellaquinone | Acidianus ambivalens | - |
fumarate + caldariellaquinol | - |
r | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Acidianus ambivalens | O73937 and O73937 and O73939 and O73940 | O73937: FAD-containing subunit SdhA, O73937: iron-sulfur subunit SdhB, O73939: subunit SdhC, O73940: subunit SdhD | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Acidianus ambivalens |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| succinate + caldariellaquinone | - |
Acidianus ambivalens | fumarate + caldariellaquinol | - |
r | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 67000 + x * 33000 + x * 28000 + x * 14000, SDS-PAGE | Acidianus ambivalens |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| succinate:quinone oxidoreductase | - |
Acidianus ambivalens |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| FAD | the enzyme complex contains one molecule of covalently bound FAD | Acidianus ambivalens | |
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Release 2023.1 (January 2023)
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