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Literature summary for 1.3.5.1 extracted from

  • Amino, H.; Wang, H.; Hirawake, H.; Saruta, F.; Mizuchi, D.; Mineki, R.; Shindo, N.; Murayama, K.; Takamiya, S.; Aoki, T.; Kojima, S.; Kita, K.
    Stage-specific isoforms of Ascaris suum complex II: the fumarate reductase of the parasitic adult and the succinate dehydrogenase of free-living larvae share a common iron-sulfur subunit (2000), Mol. Biochem. Parasitol., 106, 63-76.
    View publication on PubMed
Search for more literature for 1.3.5.1

Cloned(Commentary)

Cloned (Comment) Organism
cDNA of iron-sulfur subunit Ascaris suum
cDNA of iron-sulfur subunit Caenorhabditis elegans
cloning of the complete cDNAs for the iron-sulfur protein of complex II Caenorhabditis elegans
cloning of the complete cDNAs for the iron-sulfur protein of complex II from anaerobic adult Ascaris suum

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
 Ascaris suum 5739
-
mitochondrion of the adult parasitic nematode and of free living second stage larvae Ascaris suum 5739
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Ascaris suum complex II of adult organism muscle exhibits high fumarate reductase activity and plays a key role in anaerobic electron-transport during adaptation to their microaerobic habitat, in contrast larval complex II shows a much lower fumarate reductase activity than the adult enzyme and functions as succinate dehydrogenase in aerobic respiration ?
-
 ?

Organism

Organism UniProt Comment Textmining
Ascaris suum
-
-
-
Ascaris suum
-
 succinate dehydrogenase
-
Ascaris suum
-
 fumarate reductase
-
Caenorhabditis elegans
-
-
-

Purification (Commentary)

Purification (Comment) Organism
of larval and adult complex II, using DEAE-cellulofine column chromatography in the presence of 0.1% w/v sucrose monolaurate Ascaris suum

Source Tissue

Source Tissue Comment Organism Textmining
muscle
-
 Ascaris suum
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information complex II of adult organism muscle exhibits high fumarate reductase activity and plays a key role in anaerobic electron-transport during adaptation to their microaerobic habitat, in contrast larval complex II shows a much lower fumarate reductase activity than the adult enzyme and functions as succinate dehydrogenase in aerobic respiration Ascaris suum ?
-
 ?

Subunits

Subunits Comment Organism
? two different stage specific forms of complex II (EC 1.3.5.1) share a comme iron-sulfur subunit Ascaris suum

Cofactor

Cofactor Comment Organism Structure
cytochrome b
-
 Ascaris suum
additional information the fumarate reductase of the parasitic adult and the succinate dehydrogenase of free-living larvae share a common iron-sulfur subunit, at least the flavoprotein subunit and the small subunit of cytochrome b of the larval complex II differ from those of adult Ascaris suum
additional information the enzyme contains iron-sulfur centers Ascaris suum