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Literature summary for 1.3.3.6 extracted from

  • Okamura, M.; Ueno, T.; Tanaka, S.; Murata, Y.; Kobayashi, H.; Miyamoto, A.; Abe, M.; Fukuda, N.
    Increased expression of acyl-CoA oxidase 2 in the kidney with plasma phytanic acid and altered gut microbiota in spontaneously hypertensive rats (2021), Hypertens. Res., 44, 651-661 .
    View publication on PubMed
Search for more literature for 1.3.3.6

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Rattus norvegicus 5829
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
acyl-CoA + O2 Rattus norvegicus
-
 trans-2,3-dehydroacyl-CoA + H2O2
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
kidney
-
 Rattus norvegicus
-
renal cortex
-
 Rattus norvegicus
-
renal medulla
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acyl-CoA + O2
-
 Rattus norvegicus trans-2,3-dehydroacyl-CoA + H2O2
-
 ?

Synonyms

Synonyms Comment Organism
ACOX2
-
 Rattus norvegicus
acyl-CoA oxidase 2
-
 Rattus norvegicus

Expression

Organism Comment Expression
Rattus norvegicus increased renal isoform ACOX2 activity is associated with the onset of hypertension up

General Information

General Information Comment Organism
physiological function increased expression of isoform ACOX2 in the kidney along with increases in plasma phytanic acid and the altered gut microbiota may be involved in the oxidation in the kidney and the pathogenesis of hypertension Rattus norvegicus