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Literature summary for 1.3.3.5 extracted from
- Enzymatic oxidation of bilirubin by intestinal mucosa (1987), Biochim. Biophys. Acta, 923, 268-274.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| albumin | - |
Rattus norvegicus | |
| KCl | 50 mM, 40% inhibition | Rattus norvegicus |  |
| KCN | 30 mM, 78% inhibition | Rattus norvegicus | |
| MgCl2 | 50 mM, 52% inhibition | Rattus norvegicus | |
| NaCl | 50 mM, 17% inhibition | Rattus norvegicus | |
| NAD+ | 1 mM, 66% inhibition | Rattus norvegicus | |
| NADH | 1 mM, 72% inhibition | Rattus norvegicus | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.077 | - |
bilirubin | - |
Rattus norvegicus | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| mitochondrion | - |
Rattus norvegicus | 5739 | - |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| copper | 2 Cu2+ per protein molecule | Rattus norvegicus | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| small intestine mucosa | maximum activity in jejunum | Rattus norvegicus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 0.00051 | - |
enzyme activity in small intestine | Rattus norvegicus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| bilirubin + O2 | - |
Rattus norvegicus | biliverdin + H2O | biliverdin + colourless diazo-negative compounds, including propentdyopents | ? | |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 40 | - |
- |
Rattus norvegicus |
Temperature Stability [°C]
| Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 100 | - |
5 min, complete inactivation | Rattus norvegicus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 9 | - |
- |
Rattus norvegicus |
pH Range
| pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|
| 8 | 10 | at pH 8.0 and 10.0: about 30% of maximum activity | Rattus norvegicus |
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Release 2023.1 (January 2023)
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