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Literature summary for 1.3.3.3 extracted from

  • Sopena, Y.E.; Ferramola de Sancovich, A.M.; Sancovich, H.A.
    Hexachlorobenzene treatment on hepatic mitochondrial function parameters and intracellular coproporphyrinogen oxidase location (2008), Int. J. Toxicol., 27, 455-465.
    View publication on PubMed

Application

Application Comment Organism
medicine chronic exposure of rats to hexachlorobenzene produces an experimental model for human porphyria cutanea tarda. In digitonin-treated hexachlorobenzene mitochondria, coproporphyrinogen oxidase is free in the mitochondrial intermembrane space, whereas in normal mitochondria, 30%-50% remain anchored to the inner membrane Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion in digitonin-treated mitochondria from animals exposed to hexachlorobenzene, coproporphyrinogen oxidase is free in the mitochondrial intermembrane space, whereas in normal mitochondria, 30%-50% remain anchored to the inner membrane Rattus norvegicus 5739
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Organism

Organism UniProt Comment Textmining
Rattus norvegicus
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