Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Coproporphyrin I | 70% inhibition at 0.0195 mM | Rattus sp. | |
Coproporphyrin II | 61% inhibition at 0.0206 mM | Rattus sp. | |
coproporphyrin III | 52% inhibition at 0.0194 mM | Rattus sp. | |
Coproporphyrin IV | 30% inhibition at 0.0196 mM | Rattus sp. | |
Harderoporphyrin | 27% inhibition at 0.02 mM | Rattus sp. | |
Pentacarboxylate porphyrin III | 10% inhibition at 0.0198 mM | Rattus sp. |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00012 | - |
Coproporphyrinogen-III | - |
Rattus sp. | |
0.0009 | - |
coproporphyrinogen IV | - |
Rattus sp. | |
0.0016 | - |
Harderoporphyrinogen | - |
Rattus sp. | |
0.029 | - |
pentacarboxylate porphyrinogen III | - |
Rattus sp. |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Rattus sp. | 5739 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
coproporphyrinogen-III + O2 + 2 H+ | Rattus sp. | - |
protoporphyrinogen-IX + 2 CO2 + 2 H2O | - |
? | |
coproporphyrinogen-IV + O2 | Rattus sp. | - |
protoporphyrinogen-XIII + 2 CO2 + 2 H2O | - |
? | |
harderoporphyrinogen + O2 | Rattus sp. | - |
protoporphyrinogen IX + CO2 + H2O2 | - |
? | |
pentacarboxylate porphyrinogen III + O2 | Rattus sp. | half of the activity compared to coproporphyrinogen oxidase-III | dehydroisocoproporphyrinogen + CO2 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus sp. | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Rattus sp. | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
coproporphyrinogen-III + O2 + 2 H+ | - |
Rattus sp. | protoporphyrinogen-IX + 2 CO2 + 2 H2O | - |
? | |
coproporphyrinogen-IV + O2 | - |
Rattus sp. | protoporphyrinogen-XIII + 2 CO2 + 2 H2O | - |
? | |
harderoporphyrinogen + O2 | - |
Rattus sp. | protoporphyrinogen IX + CO2 + H2O2 | - |
? | |
harderoporphyrinogen + O2 + H+ | - |
Rattus sp. | protoporphyrinogen IX + CO2 + H2O2 | - |
r | |
pentacarboxylate porphyrinogen III + O2 | half of the activity compared to coproporphyrinogen oxidase-III | Rattus sp. | dehydroisocoproporphyrinogen + CO2 | - |
? |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0076 | - |
Coproporphyrinogen-III | competitive inhibition | Rattus sp. |