Literature summary for 1.3.1.92 extracted from

Kayani, S.I.; Shen, Q.; Ma, Y.; Fu, X.; Xie, L.; Zhong, Y.; Tiantian, C.; Pan, Q.; Li, L.; Rahman, S.U.; Sun, X.; Tang, K.
The YABBY family transcription factor AaYABBY5 directly targets cytochrome P450 monooxygenase (CYP71AV1) and double-bond reductase 2 (DBR2) involved in artemisinin biosynthesis in Artemisia annua (2019), Front. Plant Sci., 10, 1084 .

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Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
artemisinic aldehyde + NADPH + H+	Artemisia annua	-	(11R)-dihydroartemisinic aldehyde + NADP+	-	?

Organism

Organism	UniProt	Comment	Textmining
Artemisia annua	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
artemisinic aldehyde + NADPH + H+	-	Artemisia annua	(11R)-dihydroartemisinic aldehyde + NADP+	-	?

Synonyms

Synonyms	Comment	Organism
Dbr2	-	Artemisia annua
double-bond reductase 2	-	Artemisia annua

Cofactor

Cofactor	Comment	Organism	Structure
NADPH	-	Artemisia annua

Expression

Organism	Comment	Expression
Artemisia annua	YABBY5 significantly increases the activity of the promoter of the enzyme	up

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Release 2023.1 (January 2023)