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Literature summary for 1.3.1.8 extracted from

  • Erb, T.J.; Berg, I.A.; Brecht, V.; Mueller, M.; Fuchs, G.; Alber, B.E.
    Synthesis of C5-dicarboxylic acids from C2-units involving crotonyl-CoA carboxylase/reductase: the ethylmalonyl-CoA pathway (2007), Proc. Natl. Acad. Sci. USA, 104, 10631-10636.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli Cereibacter sphaeroides

Organism

Organism UniProt Comment Textmining
Cereibacter sphaeroides
-
-
-

Purification (Commentary)

Purification (Comment) Organism
DEAE-Sepharose column chromatography and Cibacron Blue column chromatography Cereibacter sphaeroides

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
crotonyl-CoA + NADPH
-
Cereibacter sphaeroides butanoyl-CoA + NADP+
-
?
additional information no activity with acetoacetyl-CoA or (R)-3-hydroxybutyryl-CoA Cereibacter sphaeroides ?
-
?

Synonyms

Synonyms Comment Organism
crotonyl-CoA reductase
-
Cereibacter sphaeroides

Cofactor

Cofactor Comment Organism Structure
NADPH
-
Cereibacter sphaeroides