Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2-nonanone | product inhibition, competitive versus trans-3-nonen-2-one | Rattus norvegicus | |
additional information | no inhibition by 9,10-phenanthroline | Rattus norvegicus | |
NADP+ | product inhibition, competitive versus NADPH | Rattus norvegicus | |
Zn2+ | - |
Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | ordered Theorell-Chance kinetic mechanism, steady-state kinetics, detailed analysis, kinetic isotopic effects | Rattus norvegicus | |
0.004 | - |
NADPH | recombinant enzyme, pH 7.2, 25°C, with substrate trans-2-nonenal | Rattus norvegicus | |
0.028 | - |
trans-3-nonen-2-one | recombinant enzyme, pH 7.2, 25°C | Rattus norvegicus | |
0.032 | - |
NADPH | recombinant enzyme, pH 7.2, 25°C, with substrate trans-3-nonen-2-one | Rattus norvegicus | |
0.078 | - |
trans-2-nonenal | recombinant enzyme, pH 7.2, 25°C | Rattus norvegicus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
additional information | enzyme contains no Zn2+ | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Rattus norvegicus | phase2/antioxidative enzyme | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
a n-alkanal + NAD(P)+ = an alk-2-enal + NAD(P)H + H+ | catalytic and kinetic mechanism | Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | phase2/antioxidative enzyme | Rattus norvegicus | ? | - |
? | |
additional information | regio- and stereochemistry of hydride transfer, overview | Rattus norvegicus | ? | - |
? | |
trans-2-nonenal + NAD(P)H | - |
Rattus norvegicus | nonanal + NAD(P)+ | - |
? | |
trans-3-nonen-2-one + NAD(P)H | - |
Rattus norvegicus | 2-nonanone + NAD(P)+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
alkenal/one oxidoreductase | - |
Rattus norvegicus |
AOR | - |
Rattus norvegicus |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
25 | - |
assay at | Rattus norvegicus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.2 | - |
assay at | Rattus norvegicus |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
additional information | - |
pH-profile | Rattus norvegicus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADH | low activity, 20fold higher activity with NADPH | Rattus norvegicus | |
NADPH | dependent on, beta-specific | Rattus norvegicus |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | product inhibition kinetics | Rattus norvegicus |