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Literature summary for 1.3.1.70 extracted from

  • Huang, B.; Qian, P.; Gao, N.; Shen, J.; Hou, S.
    Fackel interacts with gibberellic acid signaling and vernalization to mediate flowering in Arabidopsis (2017), Planta, 245, 939-950 .
    View publication on PubMed
Search for more literature for 1.3.1.70

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana Q9LDR4
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Source Tissue

Source Tissue Comment Organism Textmining
rosette leaf
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 Arabidopsis thaliana
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seedling
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 Arabidopsis thaliana
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Synonyms

Synonyms Comment Organism
C-14 reductase
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 Arabidopsis thaliana
fackel
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 Arabidopsis thaliana
fk-J3158
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 Arabidopsis thaliana

Cofactor

Cofactor Comment Organism Structure
NADPH
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 Arabidopsis thaliana

General Information

General Information Comment Organism
malfunction Arabidopsis thaliana weak mutant allele fk-J3158, impaired in the FACKEL (FK) gene, which encodes the C-14 reductase, has a long life cycle and delayed flowering time in different photoperiods. Enzyme overexpression lines display an earlier flowering phenotype than that of the wild-type, flowering time of fk-J3158 flc double mutant is significantly earlier than that of fk-J3158 under the long-day conditions. These processes might be independent of the downstream brassinosteroid pathway and the autonomous pathway. The fk-J3158 plants are more sensitive than wild-type in reducing the bolting days and total leaf number under gibberellic acid treatment. Enzyme mutation leads to an absence of endogenous gibberellic acids in fk-J3158 and FK gene expression also affected under gibberellic acid and paclobutrazol treatment. The delayed flowering time of fk-J3158 is rescued by a 3-week vernalization treatment, and the expression of flowering locus C C (FLC) is accordingly downregulated in fk-J3158. Flowering time of fk-J3158 flc double mutant is significantly earlier than that of fk-J3158 under the long-day conditions. Phenotypes, detailed overview Arabidopsis thaliana
physiological function the enzyme is involved in sterol biosynthesis, but is also involved in the flowering of Arabidopsis mainly via the gibberellin pathway and vernalization pathway. This function of the enzyme is partially dependent on the FLOWERING LOCUS C (FLC) Arabidopsis thaliana