Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.3.1.70 extracted from

  • Hata, M.; Ishii, Y.; Watanabe, E.; Uoto, K.; Kobayashi, S.; Yoshida, K.; Otani, T.; Ando, A.
    Inhibition of ergosterol synthesis by novel antifungal compounds targeting C-14 reductase (2010), Med. Mycol., 48, 613-621.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Saccharomyces cerevisiae Candida albicans

Inhibitors

Inhibitors Comment Organism Structure
4-(3-[[1-(4-bromophenyl)piperidin-4-yl](methyl)amino]-1-methoxypropyl)benzonitrile using a genetic aproach in Saccharomyces cerevisiae it is shown that ERG24 is the target enzyme of compound 4-(3-[[1-(4-bromophenyl)piperidin-4-yl](methyl)amino]-1-methoxypropyl)benzonitrile Candida albicans
amorolfine
-
Candida albicans

Organism

Organism UniProt Comment Textmining
Candida albicans
-
-
-

Synonyms

Synonyms Comment Organism
C-14 reductase
-
Candida albicans