BRENDA - Enzyme Database
show all sequences of 1.3.1.7

L- and mesotartaric acid dehydrogenase (crystalline)

Kohn, L.D.; Jakoby, W.B.; Methods Enzymol. 9, 236-240 (1966)
No PubMed abstract available

Data extracted from this reference:

Activating Compound
Activating Compound
Commentary
Organism
Structure
mercaptan
-
Pseudomonas putida
Crystallization (Commentary)
Crystallization (Commentary)
Organism
rectangular prisms
Pseudomonas putida
KM Value [mM]
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
0.06
-
NAD+
-
Pseudomonas putida
0.15
-
NAD+
-
Pseudomonas putida
0.45
-
meso-tartrate
-
Pseudomonas putida
7.2
-
L(+)-Tartrate
-
Pseudomonas putida
Localization
Localization
Commentary
Organism
GeneOntology No.
Textmining
mitochondrion
-
Rattus norvegicus
5739
-
mitochondrion
-
Bos taurus
5739
-
Metals/Ions
Metals/Ions
Commentary
Organism
Structure
Mn2+
required
Pseudomonas putida
Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
ID
meso-tartrate + NAD+
Pseudomonas sp.
-
dihydroxyfumaric acid + NADH
-
-
r
meso-tartrate + NAD+
Pseudomonas putida
-
dihydroxyfumaric acid + NADH
-
-
r
meso-tartrate + NAD+
Pseudomonas sp. A
-
dihydroxyfumaric acid + NADH
-
-
r
Organism
Organism
UniProt
Commentary
Textmining
Bos taurus
-
cow
-
Pseudomonas putida
-
-
-
Pseudomonas sp.
-
A
-
Pseudomonas sp. A
-
A
-
Rattus norvegicus
-
rat
-
Purification (Commentary)
Purification (Commentary)
Organism
-
Pseudomonas putida
Specific Activity [micromol/min/mg]
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
0.354
-
-
Pseudomonas putida
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
Substrate Product ID
dihydroxyfumaric acid + NADH
-
349356
Pseudomonas putida
meso-tartrate + NAD+
-
-
-
r
L-(+)-tartrate + NAD+
-
349356
Pseudomonas putida
(3R)-oxaloglycolate + NADH
-
-
-
?
meso-tartrate + NAD+
-
349356
Pseudomonas sp.
dihydroxyfumaric acid + NADH
-
-
-
r
meso-tartrate + NAD+
-
349356
Pseudomonas putida
dihydroxyfumaric acid + NADH
-
-
-
r
meso-tartrate + NAD+
-
349356
Pseudomonas sp. A
dihydroxyfumaric acid + NADH
-
-
-
r
pH Optimum
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
6.5
-
dihydroxyfumarate and NADH as substrate
Pseudomonas putida
8.5
-
50% of optimal activity at pH 7 and 9
Pseudomonas putida
Activating Compound (protein specific)
Activating Compound
Commentary
Organism
Structure
mercaptan
-
Pseudomonas putida
Crystallization (Commentary) (protein specific)
Crystallization
Organism
rectangular prisms
Pseudomonas putida
KM Value [mM] (protein specific)
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
0.06
-
NAD+
-
Pseudomonas putida
0.15
-
NAD+
-
Pseudomonas putida
0.45
-
meso-tartrate
-
Pseudomonas putida
7.2
-
L(+)-Tartrate
-
Pseudomonas putida
Localization (protein specific)
Localization
Commentary
Organism
GeneOntology No.
Textmining
mitochondrion
-
Rattus norvegicus
5739
-
mitochondrion
-
Bos taurus
5739
-
Metals/Ions (protein specific)
Metals/Ions
Commentary
Organism
Structure
Mn2+
required
Pseudomonas putida
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
ID
meso-tartrate + NAD+
Pseudomonas sp.
-
dihydroxyfumaric acid + NADH
-
-
r
meso-tartrate + NAD+
Pseudomonas putida
-
dihydroxyfumaric acid + NADH
-
-
r
meso-tartrate + NAD+
Pseudomonas sp. A
-
dihydroxyfumaric acid + NADH
-
-
r
Purification (Commentary) (protein specific)
Commentary
Organism
-
Pseudomonas putida
Specific Activity [micromol/min/mg] (protein specific)
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
0.354
-
-
Pseudomonas putida
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
ID
dihydroxyfumaric acid + NADH
-
349356
Pseudomonas putida
meso-tartrate + NAD+
-
-
-
r
L-(+)-tartrate + NAD+
-
349356
Pseudomonas putida
(3R)-oxaloglycolate + NADH
-
-
-
?
meso-tartrate + NAD+
-
349356
Pseudomonas sp.
dihydroxyfumaric acid + NADH
-
-
-
r
meso-tartrate + NAD+
-
349356
Pseudomonas putida
dihydroxyfumaric acid + NADH
-
-
-
r
meso-tartrate + NAD+
-
349356
Pseudomonas sp. A
dihydroxyfumaric acid + NADH
-
-
-
r
pH Optimum (protein specific)
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
6.5
-
dihydroxyfumarate and NADH as substrate
Pseudomonas putida
8.5
-
50% of optimal activity at pH 7 and 9
Pseudomonas putida
Other publictions for EC 1.3.1.7
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Synonyms
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
349359
Serfozo
Substrate determinants of the ...
Escherichia coli, Pseudomonas putida
Biochemistry
34
7517-7524
1995
-
-
1
-
-
-
-
13
-
-
-
-
-
2
-
-
1
-
-
-
-
-
18
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
13
-
-
-
-
-
-
-
1
-
-
-
-
18
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
349358
Beecher
Tartrate dehydrogenase-oxalate ...
Escherichia coli
Arch. Biochem. Biophys.
315
255-261
1994
-
-
1
-
-
-
1
8
-
-
-
-
-
1
-
-
1
1
-
-
-
-
9
-
2
-
-
-
2
-
-
-
4
-
-
-
-
-
1
4
-
-
-
-
1
-
8
-
-
-
-
-
-
-
1
-
-
-
-
9
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
287509
Do Nascimento
The stereospecificity of seque ...
Pseudomonas putida, Pseudomonas putida ATCC 17642
Biochem. J.
149
553-557
1975
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
1
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
349356
Kohn
-
L- and mesotartaric acid dehyd ...
Bos taurus, Pseudomonas sp., Pseudomonas putida, Rattus norvegicus, Pseudomonas sp. A
Methods Enzymol.
9
236-240
1966
1
-
-
1
-
-
-
4
2
1
-
3
-
9
-
-
1
-
-
-
1
-
5
-
-
-
-
-
-
2
-
-
-
-
-
-
1
-
-
-
1
-
-
-
-
-
4
2
1
-
3
-
-
-
1
-
-
1
-
5
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-