Literature summary for 1.3.1.46 extracted from

Schlieper, D.; Tiemann, K.; Barz, W.
Stereospecificity of hydrogen transfer by fungal and plant NADPH:isoflavone oxidoreductases (1990), Phytochemistry, 29, 1519-1524.

No PubMed abstract available

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Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
6,7-dihydroxy-4'-methoxyisoflavone + NADPH + H+	Fusarium solani-melongenae	-	(3S)-2-dihydrobiochanin A + NADP+	-	?

Organism

Organism	UniProt	Comment	Textmining
Fusarium solani-melongenae	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
6,7-dihydroxy-4'-methoxyisoflavone + NADPH + H+	-	Fusarium solani-melongenae	(3S)-2-dihydrobiochanin A + NADP+	-	?
6,7-dihydroxy-4'-methoxyisoflavone + NADPH + H+	trivial name biochanin A	Fusarium solani-melongenae	(3S)-2-dihydrobiochanin A + NADP+	incorporation of pro-R hydrogen from NADPH, i.e. A-specific	?

Cofactor

Cofactor	Comment	Organism	Structure
NADPH	-	Fusarium solani-melongenae

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Release 2023.1 (January 2023)