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Literature summary for 1.3.1.43 extracted from

  • Keller, B.; Keller, E.; Lingens, F.
    Arogenate dehydrogenase from Streptomyces phaeochromogenes. Purification and properties (1985), Biol. Chem. Hoppe-Seyler, 366, 1063-1066.
    View publication on PubMed

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.01
-
NAD+
-
Streptomyces phaeochromogenes
0.1
-
L-arogenate
-
Streptomyces phaeochromogenes

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
28100
-
2 * 28100, SDS-PAGE Streptomyces phaeochromogenes
66300
-
gel filtration Streptomyces phaeochromogenes

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-arogenate + NAD+ Streptomyces phaeochromogenes
-
L-tyrosine + NADH + CO2
-
?

Organism

Organism UniProt Comment Textmining
Streptomyces phaeochromogenes
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Streptomyces phaeochromogenes

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
Streptomyces phaeochromogenes
18.8
-
purified enzyme Streptomyces phaeochromogenes

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-arogenate + NAD(P)+
-
Streptomyces phaeochromogenes L-tyrosine + NAD(P)H + CO2
-
?
L-arogenate + NAD+
-
Streptomyces phaeochromogenes L-tyrosine + NADH + CO2
-
?

Subunits

Subunits Comment Organism
dimer 2 * 28100, SDS-PAGE Streptomyces phaeochromogenes

Cofactor

Cofactor Comment Organism Structure
NAD+ specific for Streptomyces phaeochromogenes