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Literature summary for 1.3.1.43 extracted from

  • Lingens, F.; Keller, E.; Keller, B.
    Arogenate dehydrogenase from Phenylobacterium immobile (1987), Methods Enzymol., 142, 513-518.
No PubMed abstract available

Inhibitors

Inhibitors Comment Organism Structure
prephenate
-
Phenylobacterium immobile

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.02
-
NAD+
-
Phenylobacterium immobile
0.91
-
L-arogenate
-
Phenylobacterium immobile

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
37700
-
2 * 37700, SDS-PAGE Phenylobacterium immobile
61700
-
gel filtration Phenylobacterium immobile

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-arogenate + NAD+ Phenylobacterium immobile
-
L-tyrosine + NADH + CO2
-
?

Organism

Organism UniProt Comment Textmining
Phenylobacterium immobile
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Phenylobacterium immobile

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
95.5
-
-
Phenylobacterium immobile

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-arogenate + NAD(P)+
-
Phenylobacterium immobile L-tyrosine + NAD(P)H + CO2
-
?
L-arogenate + NAD+
-
Phenylobacterium immobile L-tyrosine + NADH + CO2
-
?
additional information highly specific for arogenate Phenylobacterium immobile ?
-
?
prephenate + NAD(P)+ not prephenate Phenylobacterium immobile ?
-
?

Subunits

Subunits Comment Organism
dimer 2 * 37700, SDS-PAGE Phenylobacterium immobile

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
9.5
-
-
Phenylobacterium immobile